Shalini Kanagasingam
Overview
Explore the profile of Shalini Kanagasingam including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
210
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Recent Articles
1.
Singhrao S, Consoli C, Dennison S, Kanagasingam S, Welbury R
J Alzheimers Dis Rep
. 2024 Aug;
8(1):1055-1067.
PMID: 39114545
Background: Glycogen synthase-3 kinase (GSK3) is one of the major contributors of tau hyperphosphorylation linked to neurofibrillary tangles in Alzheimer's disease (AD). Objective: To determine a mechanism of GSK-3β activation...
2.
Lewis R, Kanagasingam S, Cook N, Krysmann M, Taylor K, Pisani F
Healthcare (Basel)
. 2024 May;
12(10).
PMID: 38786445
The removal of dental plaque from the gingival margins of the teeth is essential to maintaining periodontal health. Whilst it has been established that electric toothbrushes demonstrate a greater ability...
3.
See Z, Lee M, Parolia A, Kanagasingam S, Gunjal S, Patel S
Restor Dent Endod
. 2024 Mar;
49(1):e8.
PMID: 38449491
Objectives: The purpose of this study was to evaluate the effect of Dental Practicality Index (DPI) training using an online video on the treatment planning decisions and confidence level of...
4.
Cook N, Kelly A, Kanagasingam S, Tagiyeva N
Gerodontology
. 2023 Feb;
41(1):28-39.
PMID: 36790065
Objectives: The aim of this study was to explore oral health experiences and priorities in a diverse group of adults aged over 60 in North West England, an area with...
5.
Kanagasingam S, Von Ruhland C, Welbury R, Singhrao S
J Alzheimers Dis Rep
. 2023 Feb;
6(1):757-773.
PMID: 36721488
Background: Oral infection has been implicated in the possible etiology of Alzheimer's disease. Objective: To detect amyloid-β (Aβ) within microbial biofilms. Methods: Freshly extracted teeth ( = 87) with periodontal...
6.
McLean S, Cook N, Rovira-Wilde A, Patel S, Kanagasingam S
J Endod
. 2022 Dec;
49(2):155-161.
PMID: 36526106
Introduction: YouTube is one of the most used social media platforms for health care information. Misinformation and poor educational content on this platform can exacerbate public anxiety and fear of...
7.
Kanagasingam S, Von Ruhland C, Welbury R, Chukkapalli S, Singhrao S
J Alzheimers Dis Rep
. 2022 Oct;
6(1):577-587.
PMID: 36275415
Background: Cleavage of the amyloid-β protein precursor (AβPP) mediated by host secretase enzymes, releases several fragments including amyloid-β (Aβ and Aβ). Objective: To determine if conditioned medium cleaved AβPP to...
8.
Kanagasingam S, Von Ruhland C, Welbury R, Singhrao S
J Alzheimers Dis
. 2022 Aug;
89(4):1279-1291.
PMID: 36031895
Background: Tau is an established substrate for gingipains secreted by Porphyromonas gingivalis. Hyperphosphorylation of tau and neurofibrillary tangle (NFT) formation is a defining lesion of Alzheimer's disease (AD) where NFT...
9.
Harding A, Kanagasingam S, Welbury R, Singhrao S
Adv Exp Med Biol
. 2022 May;
1373:241-260.
PMID: 35612802
Periodontitis and Alzheimer's disease (AD) exist globally within the adult population. Given that the risk of AD incidence doubles within 10 years from the time of periodontal disease diagnosis, there...
10.
Liew J, Zainal Abidin I, Cook N, Kanagasingam S
Eur J Dent Educ
. 2021 Dec;
26(4):707-716.
PMID: 34936724
Introduction: Treatment decisions for a heavily restored endodontically treated tooth vary amongst clinicians owing to multitude of factors. This phenomenon not only often poses dilemmas to clinicians of different clinical...