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Shalin B Mehta

Explore the profile of Shalin B Mehta including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 908
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Recent Articles
1.
Chandler T, Guo M, Su Y, Chen J, Wu Y, Liu J, et al.
Proc Natl Acad Sci U S A . 2025 Feb; 122(8):e2406679122. PMID: 39982748
Polarized fluorescence microscopy is a valuable tool for measuring molecular orientations in biological samples, but techniques for recovering three-dimensional orientations and positions of fluorescent ensembles are limited. We report a...
2.
Hein M, Peng D, Todorova V, McCarthy F, Kim K, Liu C, et al.
Cell . 2025 Jan; 188(4):1137-1155.e20. PMID: 39742809
Defining the subcellular distribution of all human proteins and their remodeling across cellular states remains a central goal in cell biology. Here, we present a high-resolution strategy to map subcellular...
3.
Ivanov I, Hirata-Miyasaki E, Chandler T, Cheloor-Kovilakam R, Liu Z, Pradeep S, et al.
PNAS Nexus . 2024 Sep; 3(9):pgae323. PMID: 39282007
High-throughput dynamic imaging of cells and organelles is essential for understanding complex cellular responses. We report Mantis, a high-throughput 4D microscope that integrates two complementary, gentle, live-cell imaging technologies: remote-refocus...
4.
Yeh L, Ivanov I, Chandler T, Byrum J, Chhun B, Guo S, et al.
Nat Methods . 2024 Jun; 21(7):1257-1274. PMID: 38890427
The dry mass and the orientation of biomolecules can be imaged without a label by measuring their permittivity tensor (PT), which describes how biomolecules affect the phase and polarization of...
5.
De Niz M, Escobedo Garcia R, Teran Ramirez C, Pakowski Y, Abonza Y, Bialy N, et al.
J Microsc . 2024 May; 294(3):420-439. PMID: 38747464
In September 2023, the two largest bioimaging networks in the Americas, Latin America Bioimaging (LABI) and BioImaging North America (BINA), came together during a 1-week meeting in Mexico. This meeting...
6.
Chandler T, Guo M, Su Y, Chen J, Wu Y, Liu J, et al.
bioRxiv . 2024 May; PMID: 38712306
Polarized fluorescence microscopy is a valuable tool for measuring molecular orientations, but techniques for recovering three-dimensional orientations and positions of fluorescent ensembles are limited. We report a polarized dual-view light-sheet...
7.
Ivanov I, Hirata-Miyasaki E, Chandler T, Cheloor-Kovilakam R, Liu Z, Pradeep S, et al.
bioRxiv . 2024 Jan; PMID: 38187521
High-throughput dynamic imaging of cells and organelles is essential for understanding complex cellular responses. We report Mantis, a high-throughput 4D microscope that integrates two complementary, gentle, live-cell imaging technologies: remote-refocus...
8.
Byrum J, Waltari E, Janson O, Guo S, Folkesson J, Chhun B, et al.
Pathogens . 2023 May; 12(5). PMID: 37242341
A multiplexed enzyme-linked immunosorbent assay (ELISA) that simultaneously measures antibody binding to multiple antigens can extend the impact of serosurveillance studies, particularly if the assay approaches the simplicity, robustness, and...
9.
Hashemi E, Yoseph E, Tsai H, Moreno M, Yeh L, Mehta S, et al.
Cell Mol Neurobiol . 2022 Aug; 43(3):1219-1236. PMID: 35917044
Multiple sclerosis (MS) is an inflammatory-demyelinating disease of the central nervous system (CNS) mediated by aberrant auto-reactive immune responses. The current immune-modulatory therapies are unable to protect and repair immune-mediated...
10.
Ivanov I, Yeh L, Perez-Bermejo J, Byrum J, Kim J, Leonetti M, et al.
Biomed Opt Express . 2022 Jul; 13(5):3102-3119. PMID: 35774313
The spatial and angular organization of biological macromolecules is a key determinant, as well as informative readout, of their function. Correlative imaging of the dynamic spatio-angular architecture of cells and...