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Shalin B Mehta

Explore the profile of Shalin B Mehta including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 908
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Recent Articles
11.
Cho N, Cheveralls K, Brunner A, Kim K, Michaelis A, Raghavan P, et al.
Science . 2022 Mar; 375(6585):eabi6983. PMID: 35271311
Elucidating the wiring diagram of the human cell is a central goal of the postgenomic era. We combined genome engineering, confocal live-cell imaging, mass spectrometry, and data science to systematically...
12.
Wu Z, Chhun B, Popova G, Guo S, Kim C, Yeh L, et al.
Mol Biol Cell . 2022 Feb; 33(6):ar59. PMID: 35138913
A cell's shape and motion represent fundamental aspects of cell identity and can be highly predictive of function and pathology. However, automated analysis of the morphodynamic states remains challenging for...
13.
Popova G, Soliman S, Kim C, Keefe M, Hennick K, Jain S, et al.
Cell Stem Cell . 2021 Sep; 28(12):2153-2166.e6. PMID: 34536354
Microglia are resident macrophages in the brain that emerge in early development and respond to the local environment by altering their molecular and phenotypic states. Fundamental questions about microglia diversity...
14.
Fischer R, Sun X, Baird M, Hourwitz M, Seo B, Pasapera A, et al.
Proc Natl Acad Sci U S A . 2021 May; 118(22). PMID: 34031242
Contact guidance is a powerful topographical cue that induces persistent directional cell migration. Healthy tissue stroma is characterized by a meshwork of wavy extracellular matrix (ECM) fiber bundles, whereas metastasis-prone...
15.
Byrum J, Waltari E, Janson O, Guo S, Folkesson J, Chhun B, et al.
medRxiv . 2021 May; PMID: 34013298
Serology has provided valuable diagnostic and epidemiological data on antibody responses to SARS-CoV-2 in diverse patient cohorts. Deployment of high content, multiplex serology platforms across the world, including in low...
16.
Pinkard H, Stuurman N, Ivanov I, Anthony N, Ouyang W, Li B, et al.
Nat Methods . 2021 Mar; 18(3):226-228. PMID: 33674797
No abstract available.
17.
Sugizaki A, Sato K, Chiba K, Saito K, Kawagishi M, Tomabechi Y, et al.
Proc Natl Acad Sci U S A . 2021 Mar; 118(11). PMID: 33674463
Biomolecular assemblies govern the physiology of cells. Their function often depends on the changes in molecular arrangements of constituents, both in the positions and orientations. While recent advancements of fluorescence...
18.
Guo S, Yeh L, Folkesson J, Ivanov I, Krishnan A, Keefe M, et al.
Elife . 2020 Jul; 9. PMID: 32716843
We report quantitative label-free imaging with phase and polarization (QLIPP) for simultaneous measurement of density, anisotropy, and orientation of structures in unlabeled live cells and tissue slices. We combine QLIPP...
19.
Mehta S, Sheppard C
J Opt Soc Am A Opt Image Sci Vis . 2018 Aug; 35(8):1272-1282. PMID: 30110288
Explicit expressions are presented for different phase-space representations (mutual intensity, Wigner distribution function, and ambiguity function) of the partially coherent image wave field in a microscope system. These are separated...
20.
Nordenfelt P, Moore T, Mehta S, Kalappurakkal J, Swaminathan V, Koga N, et al.
Nat Commun . 2017 Dec; 8(1):2047. PMID: 29229906
Integrin αβ heterodimer cell surface receptors mediate adhesive interactions that provide traction for cell migration. Here, we test whether the integrin, when engaged to an extracellular ligand and the cytoskeleton,...