Shakila Tobwala
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Explore the profile of Shakila Tobwala including associated specialties, affiliations and a list of published articles.
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13
Citations
179
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Recent Articles
1.
Maddirala Y, Tobwala S, Karacal H, Ercal N
BMC Ophthalmol
. 2017 Apr;
17(1):54.
PMID: 28446133
Background: The present study sought to evaluate the efficacy of N-acetylcysteine amide (NACA) eye drops in reversing the cataract formation induced by sodium selenite in male Wistar rat pups. Methods:...
2.
Khayyat A, Tobwala S, Hart M, Ercal N
Toxicol Lett
. 2015 Nov;
241:133-42.
PMID: 26602168
Acetaminophen (N-acetyl-p-aminophenol, APAP) is one of the most widely used over the counter antipyretic and analgesic medications. It is safe at therapeutic doses, but its overdose can result in severe...
3.
Maddirala Y, Tobwala S, Ercal N
Brain Res
. 2015 Feb;
1608:157-66.
PMID: 25681547
Manganese (Mn) is an essential trace element required for normal cellular functioning. However, overexposure of Mn can be neurotoxic resulting in the development of manganism, a syndrome that resembles Parkinson׳s...
4.
Tobwala S, Khayyat A, Fan W, Ercal N
Exp Biol Med (Maywood)
. 2014 Sep;
240(2):261-72.
PMID: 25245075
Acetaminophen (N-acetyl-p-aminophenol, APAP) is one of the most widely used over-the-counter antipyretic analgesic medications. Despite being safe at therapeutic doses, an accidental or intentional overdose can result in severe hepatotoxicity;...
5.
Tobwala S, Fan W, Hines C, Folk W, Ercal N
BMC Complement Altern Med
. 2014 Jul;
14:271.
PMID: 25070435
Background: Sutherlandia frutescens (L.) R.Br. (SF) is a South African plant that is widely used to treat stress, infections, cancer, and chronic diseases, many of which involve oxidative stress. The...
6.
Tobwala S, Zhang X, Zheng Y, Wang H, Banks W, Ercal N
Toxicol Lett
. 2013 Apr;
220(1):1-7.
PMID: 23542817
Diesel exhaust particles (DEPs), a by-product of diesel engine exhaust (DEE), are known to produce pro-oxidative and pro-inflammatory effects, thereby leading to oxidative stress-induced damage. Given the key role of...
7.
Banerjee J, Hanson A, Gadam B, Elegbede A, Tobwala S, Ganguly B, et al.
Bioconjug Chem
. 2009 Jul;
20(7):1332-9.
PMID: 19601658
Liposomes have been widely used as a drug delivery vehicle, and currently, more than 10 liposomal formulations are approved by the Food and Drug Administration for clinical use. However, upon...
8.
Elegbede A, Banerjee J, Hanson A, Tobwala S, Ganguli B, Wang R, et al.
J Am Chem Soc
. 2008 Jul;
130(32):10633-42.
PMID: 18642903
Matrix metalloproteinases (MMPs) constitute a class of extracellular-matrix-degrading enzymes overexpressed in many cancers and contribute to the metastatic ability of the cancer cells. We have recently demonstrated that liposomal contents...
9.
Subramaniam R, Haldar M, Tobwala S, Ganguly B, Srivastava D, Mallik S
Bioorg Med Chem Lett
. 2008 Apr;
18(11):3333-7.
PMID: 18442906
A series of bis-(arylsulfonamide) hydroxamate inhibitors were synthesized. These compounds exhibit good potency against MMP-7 and MMP-9 depending on the nature, steric bulk, and substitution pattern of the substituents in...
10.
Sarkar N, Banerjee J, Hanson A, Elegbede A, Rosendahl T, Krueger A, et al.
Bioconjug Chem
. 2007 Dec;
19(1):57-64.
PMID: 18078309
We offer a novel methodology for formulating liposomes by incorporating sequence-specific collagen-mimetic peptides such that they are specifically "uncorked" by a matrix metalloproteinase, MMP-9. By encapsulating carboxyfluorescein (as a self-quenching...