Shaista Hayat
Overview
Explore the profile of Shaista Hayat including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
266
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Recent Articles
1.
B lymphocyte responses in Parkinson's disease and their possible significance in disease progression
Scott K, Chong Y, Park S, Wijeyekoon R, Hayat S, Mathews R, et al.
Brain Commun
. 2023 Mar;
5(2):fcad060.
PMID: 36993946
Inflammation contributes to Parkinson's disease pathogenesis. We hypothesized that B lymphocytes are involved in Parkinson's disease progression. We measured antibodies to alpha-synuclein and tau in serum from patients with rapid...
2.
Wijeyekoon R, Kronenberg-Versteeg D, Scott K, Hayat S, Kuan W, Evans J, et al.
Brain Behav Immun
. 2020 Feb;
87:473-488.
PMID: 32006615
The innate immune system is implicated in Parkinson's disease (PD), but peripheral in-vivo clinical evidence of the components and driving mechanisms involved and their relationship with clinical heterogeneity and progression...
3.
White A, Wijeyekoon R, Scott K, Gunawardana N, Hayat S, Solim I, et al.
Front Neurol
. 2018 Dec;
9:946.
PMID: 30524354
The immune system is activated in Parkinson's Disease (PD), as evidenced by neuroinflammatory changes within the brain as well as elevated immune markers in peripheral blood. Furthermore, inflammatory cytokine levels...
4.
Wijeyekoon R, Kronenberg-Versteeg D, Scott K, Hayat S, Jones J, Clatworthy M, et al.
Front Neurol
. 2018 Nov;
9:870.
PMID: 30386290
Increasing evidence implicates involvement of the innate immune system in the initiation and progression of Parkinson's disease (PD). Monocytes and monocyte-derived cells perform a number of functions, such as phagocytosis,...
5.
Stott S, Hayat S, Carnwath T, Garas S, Sleeman J, Barker R
PLoS One
. 2017 Feb;
12(2):e0171748.
PMID: 28182766
Parkinson's disease (PD) is a progressive neurodegenerative condition that is characterised by the loss of specific populations of neurons in the brain. The mechanisms underlying this selective cell death are...
6.
Balmanno K, Chell S, Gillings A, Hayat S, Cook S
Int J Cancer
. 2009 Jul;
125(10):2332-41.
PMID: 19637312
Mutations in KRAS or BRAF frequently manifest in constitutive activation of the MEK1/2-ERK1/2 signalling pathway. The MEK1/2-selective inhibitor, AZD6244 (ARRY-142886), blocks ERK1/2 activation and is currently undergoing clinical evaluation. Tumour...
7.
Arkell R, Dickinson R, Squires M, Hayat S, Keyse S, Cook S
Cell Signal
. 2008 Feb;
20(5):836-43.
PMID: 18280112
Extracellular signal-regulated kinase-1 and -2 (ERK1/2) are activated by dual threonine and tyrosine phosphorylation of a TEY motif. The highly related kinase ERK5 is also activated by phosphorylation at a...
8.
Hayat S, Williams R, Rattray M
J Psychopharmacol
. 2006 Mar;
20(2):257-63.
PMID: 16510483
There is much evidence from animal studies that the recreational drug MDMA is a selective toxin which damages serotonin nerve terminals and axons. These in vivo studies show that an...
9.
Kumar R, Hayat S, Felts P, Bunting S, Wigley C
Glia
. 2004 Dec;
50(1):12-20.
PMID: 15599940
We demonstrate that there are significantly more p75 neurotrophin receptor- (NTR)-expressing cells in olfactory ensheathing cell (OEC) primary cultures from olfactory nerve rootlets (ONR), but a greater proportion of O4...
10.
Davies R, Hayat S, Wigley C, Robbins J
Brain Res
. 2004 Sep;
1023(1):154-6.
PMID: 15364031
Pharmacological characterisation of the calcium influx pathway in olfactory ensheathing cells (OECs) was performed using Indo-1 calcium microfluorometry. Our previous work has implicated this pathway in olfactory ensheathing cell support...