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Shairaz Baksh

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Articles 46
Citations 1334
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Recent Articles
1.
Larochelle J, Howell J, Yang C, Liu L, Gunraj R, Stansbury S, et al.
Exp Neurol . 2024 May; 377:114812. PMID: 38729551
Ischemic stroke induces a debilitating neurological insult, where inflammatory processes contribute greatly to the expansion and growth of the injury. Receptor-interacting protein kinase 2 (RIPK2) is most well-known for its...
2.
Salla M, Karaki N, El Kaderi B, Ayoub A, Younes S, Abou Chahla M, et al.
Pharmaceutics . 2024 Apr; 16(4). PMID: 38675230
Overcoming the limited bioavailability and extensive metabolism of effective in vitro drugs remains a challenge that limits the translation of promising drugs into clinical trials. Resveratrol, despite its well-reported therapeutic...
3.
Salla M, Guo J, Joshi H, Gordon M, Dooky H, Lai J, et al.
Int J Mol Sci . 2023 Mar; 24(6). PMID: 36983040
Persistent inflammation can trigger altered epigenetic, inflammatory, and bioenergetic states. Inflammatory bowel disease (IBD) is an idiopathic disease characterized by chronic inflammation of the gastrointestinal tract, with evidence of subsequent...
4.
Baksh S, Volodko N, Soucie M, Geier S, Diep A, Rozak K, et al.
Diagn Microbiol Infect Dis . 2021 Jul; 101(2):115458. PMID: 34274751
We describe an extractionless real-time reverse transcriptase-PCR (rRT-PCR) protocol for SARS-CoV-2 nucleic acid detection using heat as an accurate cost-effective high-capacity solution to COVID-19 testing. We present the effect of...
5.
Salla M, Pandya V, Bhullar K, Kerek E, Wong Y, Losch R, et al.
Molecules . 2020 Aug; 25(17). PMID: 32847114
Resveratrol (3,4,5-Trihydroxy-trans-stilbene) is a naturally occurring polyphenol that exhibits beneficial pleiotropic health effects. It is one of the most promising natural molecules in the prevention and treatment of chronic diseases...
6.
Mann J, Githaka J, Buckland T, Yang N, Montpetit R, Patel N, et al.
Oncogene . 2019 Jan; 38(18):3325-3339. PMID: 30635657
The Bcl-2-associated death promoter BAD is a prognostic indicator for good clinical outcome of breast cancer patients; however, whether BAD affects breast cancer biology is unknown. Here we showed that...
7.
Zare A, Petrova A, Agoumi M, Armstrong H, Bigras G, Tonkin K, et al.
Cancers (Basel) . 2018 Nov; 10(11). PMID: 30405083
The authors wish to make the following correction to their paper [...].
8.
Zaidi D, Huynh H, Carroll M, Baksh S, Wine E
Clin Exp Gastroenterol . 2018 Jun; 11:217-231. PMID: 29881302
Purpose: A significant feature of pediatric inflammatory bowel diseases (IBD), which include Crohn disease (CD), and ulcerative colitis (UC), is failure to suppress inflammation. The inability to regulate inflammation renders...
9.
Zare A, Petrova A, Agoumi M, Amstrong H, Bigras G, Tonkin K, et al.
Cancers (Basel) . 2018 Jun; 10(6). PMID: 29874851
Inflammatory breast cancer (IBC) is a rare and aggressive form of breast cancer that is associated with significantly high mortality. In spite of advances in IBC diagnoses, the prognosis is...
10.
Salla M, Aguayo-Ortiz R, Danmaliki G, Zare A, Said A, Moore J, et al.
J Pharmacol Exp Ther . 2018 Mar; 365(2):354-367. PMID: 29555876
Receptor-interacting protein kinase 2 (RIP2 or RICK, herein referred to as RIPK2) is linked to the pathogen pathway that activates nuclear factor -light-chain-enhancer of activated B cells (NFB) and autophagic...