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Shaik O Rahaman

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Articles 46
Citations 697
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Recent Articles
1.
Hong L, Yue H, Cai D, DeHart A, Toloza-Alvarez G, Du L, et al.
Cardiovasc Ther . 2025 Jan; 2024:1129181. PMID: 39742002
Thymidine phosphorylase (TYMP) promotes platelet activation and thrombosis while suppressing vascular smooth muscle cell (VSMC) proliferation. Both processes are central to the development and progression of abdominal aortic aneurysms (AAAs)....
2.
Dutta B, Rahaman S, Mukherjee P, Rahaman S
J Am Heart Assoc . 2024 Dec; 14(1):e037931. PMID: 39719407
Background: Aortic valve stenosis (AVS) is a progressive disease characterized by fibrosis, inflammation, calcification, and stiffening of the aortic valve leaflets, leading to disrupted blood flow. If untreated, AVS can...
3.
Mukherjee P, Mahanty M, Dutta B, Rahaman S, Sankaran K, Rahaman S
bioRxiv . 2024 Nov; PMID: 39574752
As aortic valve stenosis (AVS) progresses, the valve tissue also stiffens. This increase in tissue stiffness causes the valvular interstitial cells (VICs) to transform into myofibroblasts in response. VIC-to-myofibroblast differentiation...
4.
Rahaman S, Dutta B, Rahaman S
bioRxiv . 2024 Nov; PMID: 39574735
Cardiovascular disease is the number one cause of death in the developed world and atherosclerosis, a chronic arterial disease, is the most dominant underlying pathology. Epidemiologic and experimental studies suggest...
5.
Dutta B, Mahanty M, Kesavalu L, Rahaman S
Front Immunol . 2024 Oct; 15:1437540. PMID: 39403372
Persistent inflammation is a major contributor in the development of various inflammatory diseases like atherosclerosis. Our study investigates how transient receptor potential vanilloid 4 (TRPV4), a mechanosensitive ion channel, interacts...
6.
Mahanty M, Dutta B, Ou W, Zhu X, Bromberg J, He X, et al.
Biomaterials . 2024 Oct; 314:122855. PMID: 39362025
Host recognition and immune-mediated foreign body response (FBR) to biomaterials can adversely affect the functionality of implanted materials. FBR presents a complex bioengineering and medical challenge due to the lack...
7.
Aravindraja C, Jeepipalli S, Duncan W, Vekariya K, Rahaman S, Chan E, et al.
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38892405
(, Sg) is one of the early colonizing, supragingival commensal bacterium normally associated with oral health in human dental plaque. MicroRNAs (miRNAs) play an important role in the inflammation-mediated pathways...
8.
Mao Y, Ma P, Li T, Liu H, Zhao X, Liu S, et al.
Nat Commun . 2024 May; 15(1):3893. PMID: 38719799
Maintaining food safety and quality is critical for public health and food security. Conventional food preservation methods, such as pasteurization and dehydration, often change the overall organoleptic quality of the...
9.
Mahanty M, Dutta B, Ou W, Zhu X, Bromberg J, He X, et al.
bioRxiv . 2024 Apr; PMID: 38617341
Host recognition and immune-mediated foreign body response (FBR) to biomaterials can adversely affect the functionality of implanted materials. To identify key targets underlying the generation of FBR, here we perform...
10.
Dutta B, Mahanty M, Kesavalu L, Rahaman S
bioRxiv . 2024 Apr; PMID: 38617263
Persistent inflammation is a major contributor in the development of various inflammatory diseases like atherosclerosis. Our study investigates how transient receptor potential vanilloid 4 (TRPV4), a mechanosensitive ion channel, interacts...