Shahana S Mahajan
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Explore the profile of Shahana S Mahajan including associated specialties, affiliations and a list of published articles.
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8
Citations
108
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Recent Articles
1.
Kang M, Rao P, Matsui H, Mahajan S
Int J Mol Sci
. 2022 Jul;
23(14).
PMID: 35887290
Although osteosarcoma is the most common primary malignant bone tumor, chemotherapeutic drugs and treatment have failed to increase the five-year survival rate over the last three decades. We previously demonstrated...
2.
Blyufer A, Lhamo S, Tam C, Tariq I, Thavornwatanayong T, Mahajan S
Int J Oncol
. 2021 Oct;
59(5).
PMID: 34713302
Riluzole, a glutamate release inhibitor, has been in use for the treatment of amyotrophic lateral sclerosis for over two decades since its approval by the Food and Drug Administration. Recently,...
3.
Raghubir M, Azeem S, Hasnat R, Rahman C, Wong L, Yan S, et al.
Sci Rep
. 2021 Oct;
11(1):20974.
PMID: 34697383
Our lab has previously demonstrated Riluzole to be an effective drug in inhibiting proliferation and inducing apoptosis in both human and mouse osteosarcoma. Yes-associated protein is a transcription co-activator, known...
4.
Liao S, Ruiz Y, Gulzar H, Yelskaya Z, Ait Taouit L, Houssou M, et al.
PLoS One
. 2017 Feb;
12(2):e0171256.
PMID: 28231291
Osteosarcomas are malignant tumors of bone, most commonly seen in children and adolescents. Despite advances in modern medicine, the poor survival rate of metastatic osteosarcoma has not improved in two...
5.
Yelskaya Z, Carrillo V, Dubisz E, Gulzar H, Morgan D, Mahajan S
PLoS One
. 2013 Jun;
8(5):e64588.
PMID: 23724064
Glioblastomas exploit various molecular pathways to promote glutamate- dependent growth by activating the AMPA (2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl) propanoic acid) receptor, the group II metabotropic glutamate receptor, mGluR, and the epidermal growth factor...
6.
Tukey D, Ferreira J, Antoine S, DAmour J, Ninan I, Cabeza de Vaca S, et al.
J Neurosci
. 2013 Apr;
33(14):6123-32.
PMID: 23554493
The mechanisms by which natural rewards such as sugar affect synaptic transmission and behavior are largely unexplored. Here, we investigate regulation of nucleus accumbens synapses by sucrose intake. Previous studies...
7.
Mahajan S, Johnson K, Wilson A
J Cell Physiol
. 2002 Dec;
194(2):117-26.
PMID: 12494450
HCF-1 functions as a coactivator for herpes simplex virus VP16 and a number of mammalian transcription factors. Mature HCF-1 is composed of two subunits generated by proteolytic cleavage of a...
8.
Mahajan S, Little M, Vazquez R, Wilson A
J Biol Chem
. 2002 Sep;
277(46):44292-9.
PMID: 12235138
HCF-1 is a cellular protein required by VP16 to activate the herpes simplex virus (HSV) immediate-early genes. VP16 is a component of the viral tegument and, after release into the...