Seungyeul Yoo
Overview
Explore the profile of Seungyeul Yoo including associated specialties, affiliations and a list of published articles.
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32
Citations
2146
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Recent Articles
11.
Cao L, Huang C, Zhou D, Hu Y, Lih T, Savage S, et al.
Cell
. 2021 Sep;
184(19):5031-5052.e26.
PMID: 34534465
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient survival. Toward understanding the underlying molecular alterations that drive PDAC oncogenesis, we conducted comprehensive proteogenomic analysis of 140...
12.
Yoo S, Shi Z, Wen B, Kho S, Pan R, Feng H, et al.
Patterns (N Y)
. 2021 May;
2(5):100245.
PMID: 34036290
Sample mislabeling or misannotation has been a long-standing problem in scientific research, particularly prevalent in large-scale, multi-omic studies due to the complexity of multi-omic workflows. There exists an urgent need...
13.
Wang L, Karpova A, Gritsenko M, Kyle J, Cao S, Li Y, et al.
Cancer Cell
. 2021 Feb;
39(4):509-528.e20.
PMID: 33577785
Glioblastoma (GBM) is the most aggressive nervous system cancer. Understanding its molecular pathogenesis is crucial to improving diagnosis and treatment. Integrated analysis of genomic, proteomic, post-translational modification and metabolomic data...
14.
Patel A, Yoo S, Kong R, Sato T, Sinha A, Karam S, et al.
Sci Adv
. 2021 Jan;
7(5).
PMID: 33514539
Comprehensive genomic analyses of small cell lung cancer (SCLC) have revealed frequent mutually exclusive genomic amplification of MYC family members. Hence, it has been long suggested that they are functionally...
15.
Huang C, Chen L, Savage S, Eguez R, Dou Y, Li Y, et al.
Cancer Cell
. 2021 Jan;
39(3):361-379.e16.
PMID: 33417831
We present a proteogenomic study of 108 human papilloma virus (HPV)-negative head and neck squamous cell carcinomas (HNSCCs). Proteomic analysis systematically catalogs HNSCC-associated proteins and phosphosites, prioritizes copy number drivers,...
16.
Petralia F, Tignor N, Reva B, Koptyra M, Chowdhury S, Rykunov D, et al.
Cell
. 2020 Nov;
183(7):1962-1985.e31.
PMID: 33242424
We report a comprehensive proteogenomics analysis, including whole-genome sequencing, RNA sequencing, and proteomics and phosphoproteomics profiling, of 218 tumors across 7 histological types of childhood brain cancer: low-grade glioma (n ...
17.
Gillette M, Satpathy S, Cao S, Dhanasekaran S, Vasaikar S, Krug K, et al.
Cell
. 2020 Jul;
182(1):200-225.e35.
PMID: 32649874
To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and 101 matched normal adjacent tissues (NATs) incorporating genomics,...
18.
Wang L, Sebra R, Sfakianos J, Allette K, Wang W, Yoo S, et al.
Genome Med
. 2020 Mar;
12(1):24.
PMID: 32111252
Background: Patient stratification based on molecular subtypes is an important strategy for cancer precision medicine. Deriving clinically informative cancer molecular subtypes from transcriptomic data generated on whole tumor tissue samples...
19.
Clark D, Dhanasekaran S, Petralia F, Pan J, Song X, Hu Y, et al.
Cell
. 2020 Jan;
180(1):207.
PMID: 31923397
No abstract available.
20.
Clark D, Dhanasekaran S, Petralia F, Pan J, Song X, Hu Y, et al.
Cell
. 2019 Nov;
179(4):964-983.e31.
PMID: 31675502
To elucidate the deregulated functional modules that drive clear cell renal cell carcinoma (ccRCC), we performed comprehensive genomic, epigenomic, transcriptomic, proteomic, and phosphoproteomic characterization of treatment-naive ccRCC and paired normal...