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Seungyeul Yoo

Explore the profile of Seungyeul Yoo including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 2146
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Recent Articles
1.
Yoo S, Patel A, Karam S, Zhong Y, Wang L, Jiang F, et al.
J Hematol Oncol . 2025 Feb; 18(1):14. PMID: 39910394
Small cell lung cancer (SCLC) is an aggressive and heterogeneous subtype, representing 15% of lung cancer cases. Although SCLC initially responds to etoposide and platinum (EP) chemotherapy, nearly all patients...
2.
Chowdhury S, Kennedy J, Ivey R, Murillo O, Hosseini N, Song X, et al.
Cell . 2024 Feb; 187(4):1016. PMID: 38364782
No abstract available.
3.
Chowdhury S, Kennedy J, Ivey R, Murillo O, Hosseini N, Song X, et al.
Cell . 2023 Aug; 186(16):3476-3498.e35. PMID: 37541199
To improve the understanding of chemo-refractory high-grade serous ovarian cancers (HGSOCs), we characterized the proteogenomic landscape of 242 (refractory and sensitive) HGSOCs, representing one discovery and two validation cohorts across...
4.
Choi I, Wang M, Yoo S, Xu P, Seegobin S, Li X, et al.
Nat Cell Biol . 2023 May; 25(7):963-974. PMID: 37231161
Dysfunctional autophagy has been implicated in the pathogenesis of Alzheimer's disease (AD). Previous evidence suggested disruptions of multiple stages of the autophagy-lysosomal pathway in affected neurons. However, whether and how...
5.
Seo W, Yoo S, Zhong Y, Lee S, Woo S, Choi H, et al.
J Hematol Oncol . 2022 Oct; 15(1):156. PMID: 36289517
Acute myeloid leukemia (AML) is an aggressive blood cancer with poor clinical outcomes. Emerging data suggest that mitochondrial oxidative phosphorylation (mtOXPHOS) plays a significant role in AML tumorigenesis, progression, and...
6.
Kong R, Patel A, Sato T, Jiang F, Yoo S, Bao L, et al.
Am J Respir Crit Care Med . 2022 Jul; 206(12):1480-1494. PMID: 35848993
The current molecular classification of small-cell lung cancer (SCLC) on the basis of the expression of four lineage transcription factors still leaves its major subtype SCLC-A as a heterogeneous group,...
7.
Wang W, Chen Y, Wu L, Zhang Y, Yoo S, Chen Q, et al.
BMC Med Genomics . 2022 Jun; 15(1):134. PMID: 35710421
Background: Hepatitis B virus (HBV) related hepatocellular carcinoma (HCC) is heterogeneous and frequently contains multifocal tumors, but how the multifocal tumors relate to each other in terms of HBV integration...
8.
Yoo S, Sinha A, Yang D, Altorki N, Tandon R, Wang W, et al.
Nat Commun . 2022 Mar; 13(1):1592. PMID: 35332150
Here we focus on the molecular characterization of clinically significant histological subtypes of early-stage lung adenocarcinoma (esLUAD), which is the most common histological subtype of lung cancer. Within lung adenocarcinoma,...
9.
Yu H, Tuminello S, Alpert N, van Gerwen M, Yoo S, Mulholland D, et al.
Carcinogenesis . 2022 Mar; 43(6):528-537. PMID: 35239955
There is increased incidence of prostate cancer (PC) among World Trade Center (WTC)-exposed responders and community members, with preliminary evidence suggestive of more aggressive disease. While previous research is supportive...
10.
Sinha A, Zou Y, Patel A, Yoo S, Jiang F, Sato T, et al.
Cancers (Basel) . 2022 Feb; 14(3). PMID: 35158979
Lung cancer is the most common cause of cancer-related deaths in both men and women, accounting for one-quarter of total cancer-related mortality globally. Lung adenocarcinoma is the major subtype of...