Seung-Shick Shin
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Explore the profile of Seung-Shick Shin including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
694
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Recent Articles
11.
Shin S, Jeong B, Wall B, Li J, Shan N, Wen Y, et al.
Oncogenesis
. 2018 Nov;
7(11):86.
PMID: 30425240
Our research group demonstrated that riluzole, an inhibitor of glutamatergic signaling reduced melanoma cell proliferation in vitro and tumor progression in vivo. The underlying mechanisms of riluzole are largely unknown....
12.
Shin S, Ko M, Park Y, Hwang B, Lyea Park S, Kim W, et al.
EXCLI J
. 2018 Jul;
17:531-543.
PMID: 30034317
Hydrangenol is a dihydroisocoumarin that is mainly obtained from . Recently, hydrangenol has garnered attention since several studies have reported that it has anti-inflammatory, anti-allergic, anti-diabetic, and anti-malarial activities. However,...
13.
Shin S, Noh D, Hwang B, Lee J, Lyea Park S, Park S, et al.
Int J Nanomedicine
. 2018 Jun;
13:3295-3310.
PMID: 29910616
Background: Although the diverse biological properties of nanoparticles have been studied intensively, research into their mechanism of action is relatively rare. In this study, we investigated the molecular mechanisms of...
14.
Shin S, Song J, Hwang B, Lyea Park S, Kim W, Park S, et al.
Food Nutr Res
. 2017 Jul;
61(1):1338918.
PMID: 28680385
: Diallyl trisulfide (DATS), a bioactive sulfur compound in garlic, has been highlighted due to its strong anti-carcinogenic activity. : The current study investigated the molecular mechanism of garlic-derived DATS...
15.
Shin S, Song J, Hwang B, Noh D, Lyea Park S, Kim W, et al.
PLoS One
. 2017 Feb;
12(2):e0171860.
PMID: 28187175
Although recent studies have demonstrated the anti-tumor effects of garlic extract (GE), the exact molecular mechanism is still unclear. In this study, we investigated the molecular mechanism associated with the...
16.
Shin S, Won S, Noh D, Hwang B, Kim W, Moon S
Drug Dev Res
. 2017 Feb;
78(2):81-90.
PMID: 28176369
Preclinical Research Previous studies have shown that morin exerts diverse pharmacological activities. In this study, we investigated the inhibitory activity of morin on bladder cancer EJ cells. Morin significantly inhibited...
17.
Shin S, Park S, Hwang B, Moon B, Kim W, Kim W, et al.
Oncol Rep
. 2016 Aug;
36(4):2313-20.
PMID: 27573859
Cancers often utilize microRNAs to suppress tumor suppressor genes, thus facilitating their potential for growth and invasion. In the present study, we report the novel findings that miR-892b inhibits proliferation,...
18.
Shin S, Park S, Hwang B, Kim W, Choi Y, Kim W, et al.
Oncol Rep
. 2016 Aug;
36(4):2421-9.
PMID: 27513725
Despite the clinical significance of tumorigenesis, little is known about the cellular signaling networks of microRNAs (miRs). Here we report a new finding that mir‑106a regulates the proliferation, migration, and...
19.
Rosenberg S, Niglio S, Salehomoum N, Chan J, Jeong B, Wen Y, et al.
Transl Oncol
. 2015 Mar;
8(1):1-9.
PMID: 25749171
Our group has previously reported that the majority of human melanomas (>60%) express the metabotropic glutamate receptor 1 (GRM1) and that the glutamate release inhibitor riluzole, a drug currently used...
20.
Teh J, Shah R, Shin S, Wen Y, Mehnert J, Goydos J, et al.
Pigment Cell Melanoma Res
. 2014 Mar;
27(4):621-9.
PMID: 24628914
Our laboratory previously described the oncogenic properties of metabotropic glutamate receptor 1 (mGluR1) in melanocytes. mGluR1 transformed immortalized mouse melanocytes in vitro and induced vigorous tumor formation in vivo. Subsequently,...