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Seung-Hun Baek

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Articles 18
Citations 583
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Recent Articles
1.
Lee S, Baek S, Hong M, Lee J, Cho E, Lee J, et al.
Tuberc Respir Dis (Seoul) . 2022 Feb; 85(3):264-272. PMID: 35196443
Background: The current conventional drug susceptibility test (DST) for Mycobacterium tuberculosis (Mtb) takes several weeks of incubation to obtain results. As a rapid method, molecular DST requires only a few...
2.
Mesman A, Baek S, Huang C, Kim Y, Cho S, Ioerger T, et al.
J Clin Med . 2021 Aug; 10(15). PMID: 34362035
An estimated 15-20% of patients who are treated for pulmonary tuberculosis (TB) are culture-negative at the time of diagnosis. Recent work has focused on the existence of differentially detectable ()...
3.
Lee J, Shin S, Cho S, Baek S, Kim D, Park K
J Arthroplasty . 2019 Nov; 35(3):864-869. PMID: 31708292
Background: Antibiotic-loaded bone cement (ALBC) is used to deliver antimycobacterial agents into the focal lesion of musculoskeletal tuberculosis. Although kanamycin is currently used as an antimycobacterial agent for the treatment...
4.
Bellerose M, Baek S, Huang C, Moss C, Koh E, Proulx M, et al.
mBio . 2019 Aug; 10(4). PMID: 31363023
Despite the administration of multiple drugs that are highly effective , tuberculosis (TB) treatment requires prolonged drug administration and is confounded by the emergence of drug-resistant strains. To understand the...
5.
Rittershaus E, Baek S, Krieger I, Nelson S, Cheng Y, Nambi S, et al.
Cell Chem Biol . 2018 Oct; 25(12):1495-1505.e3. PMID: 30318462
Upon inhibition of respiration, which occurs in hypoxic or nitric oxide-containing host microenvironments, Mycobacterium tuberculosis (Mtb) adopts a non-replicating "quiescent" state and becomes relatively unresponsive to antibiotic treatment. We used...
6.
Lee J, Han C, Cho S, Yang I, Lee W, Baek S, et al.
Clin Orthop Relat Res . 2017 Aug; 475(11):2795-2804. PMID: 28795294
Background: Antibiotic-loaded bone cement is accepted as an effective treatment modality for musculoskeletal tuberculosis. However, comparative information regarding combinations and concentrations of second-line antimycobacterial drugs, such as streptomycin and amoxicillin...
7.
Park S, Baek S, Cho S, Jang Y, Kim A, Choi I
Front Cell Infect Microbiol . 2017 Jul; 7:314. PMID: 28752079
There is a substantial need for biomarkers to distinguish latent stage from active infections, for predicting disease progression. To induce the reactivation of tuberculosis, we present a new experimental animal...
8.
Yoon J, Seo A, Kim J, Lee C, Baek S, Kim S, et al.
PLoS One . 2017 Mar; 12(3):e0174361. PMID: 28355234
We aimed to estimate the interrelation between preoperative deltoid muscle status by measuring the 3-dimensional deltoid muscle volume and postoperative functional outcomes after reverse total shoulder arthroplasty(RTSA). Thirty-five patients who...
9.
Shell S, Prestwich E, Baek S, Shah R, Sassetti C, Dedon P, et al.
PLoS Pathog . 2013 Jul; 9(7):e1003419. PMID: 23853579
DNA methylation regulates gene expression in many organisms. In eukaryotes, DNA methylation is associated with gene repression, while it exerts both activating and repressive effects in the Proteobacteria through largely...
10.
Rittershaus E, Baek S, Sassetti C
Cell Host Microbe . 2013 Jun; 13(6):643-51. PMID: 23768489
All microorganisms are exposed to periodic stresses that inhibit growth. Many bacteria and fungi weather these periods by entering a hardy, nonreplicating state, often termed quiescence or dormancy. When this...