Seth A Peng
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Explore the profile of Seth A Peng including associated specialties, affiliations and a list of published articles.
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10
Citations
204
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Recent Articles
1.
Merkhassine M, Coch R, Frederick C, Bennett L, Peng S, Morse B, et al.
J Endocrinol
. 2024 May;
262(2).
PMID: 38814331
Glucagon plays a central role in amino acid (AA) homeostasis. The dog is an established model of glucagon biology, and recently, metabolomic changes in people associated with glucagon infusions have...
2.
Watson N, Patel R, Kean C, Veazey J, Oyesola O, Laniewski N, et al.
Sci Immunol
. 2024 Feb;
9(92):eadf8776.
PMID: 38394230
CD8 T cells are classically recognized as adaptive lymphocytes based on their ability to recognize specific foreign antigens and mount memory responses. However, recent studies indicate that some antigen-inexperienced CD8...
3.
Smita S, Webb L, Mooney B, Fruh S, Oyesola O, Matheson M, et al.
Parasite Immunol
. 2023 Jul;
45(8):e12999.
PMID: 37415265
Intestinal helminth infection promotes a Type 2 inflammatory response in resistant C57BL/6 mice that is essential for worm clearance. The study of inbred mouse strains has revealed factors that are...
4.
Holm S, Peng S, Holter M, Cummings B, Loftus J
Am J Vet Res
. 2023 Feb;
84(4).
PMID: 36773290
Objective: To compare plasma concentrations of glucagon and glucagon-like peptide-1 (GLP-1) between healthy dogs and dogs with aminoaciduric canine hypoaminoacidemic hepatopathy syndrome (ACHES) dogs. Animals: Privately owned healthy (n =...
5.
Oyesola O, Shanahan M, Kanke M, Mooney B, Webb L, Smita S, et al.
J Exp Med
. 2021 Jul;
218(9).
PMID: 34283207
Type 2 inflammation is associated with epithelial cell responses, including goblet cell hyperplasia, that promote worm expulsion during intestinal helminth infection. How these epithelial responses are regulated remains incompletely understood....
6.
Fruh S, Saikia M, Eule J, Mazulis C, Miller J, Cowulich J, et al.
Vet Immunol Immunopathol
. 2020 Feb;
221:110015.
PMID: 32058160
Atopic dermatitis (AD) is an allergic skin disease that causes significant morbidity and affects multiple species. AD is highly prevalent in companion dogs, and the clinical management of the disease...
7.
Oyesola O, Duque C, Huang L, Larson E, Fruh S, Webb L, et al.
J Immunol
. 2020 Jan;
204(4):1001-1011.
PMID: 31900341
Group 2 innate lymphoid cells (ILC2s) are rare innate immune cells that accumulate in tissues during allergy and helminth infection, performing critical effector functions that drive type 2 inflammation. ILC2s...
8.
Mick P, Peng S, Loftus J
Front Vet Sci
. 2019 Aug;
6:247.
PMID: 31417914
Low vitamin D increases the risk of immune-mediated disease (IMD) in human beings and rodent models. Vitamin D metabolites, particularly 1,25(OH)2D3, modulate gene expression of immune cells and may attenuate...
9.
Webb L, Oyesola O, Fruh S, Kamynina E, Still K, Patel R, et al.
J Exp Med
. 2019 Apr;
216(6):1268-1279.
PMID: 30975892
Type 2 inflammation drives the clearance of gastrointestinal helminth parasites, which infect over two billion people worldwide. Basophils are innate immune cells that support host-protective type 2 inflammation during murine...
10.
Smith N, Patel R, Reynaldi A, Grenier J, Wang J, Watson N, et al.
Cell
. 2018 Jun;
174(1):117-130.e14.
PMID: 29909981
Heterogeneity is a hallmark feature of the adaptive immune system in vertebrates. Following infection, naive T cells differentiate into various subsets of effector and memory T cells, which help to...