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Seth-Frerich Fobian

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Fobian S, Amin M, Sacchetti A, Oei A, Ten Hagen T
J Control Release . 2025 Jan; 379:236-250. PMID: 39798703
The recent approval of pembrolizumab in recurrent or metastatic cervical cancer warrants further investigations into the usefulness of immunotherapies for more durable and less radical interventions. In this study, the...
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Petzer M, Fobian S, Gulumian M, Steenkamp V, Cordier W
Pharmacol Res Perspect . 2024 Dec; 13(1):e70051. PMID: 39725610
Gold nanoparticles (AuNPs) present with unique physicochemical features and potential for functionalization as anticancer agents. Three-dimensional spheroid models can be used to afford greater tissue representation due to their heterogeneous...
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Cheng Z, Fobian S, Gurrieri E, Amin M, DAgostino V, Falahati M, et al.
J Hematol Oncol . 2024 Jul; 17(1):53. PMID: 39030582
Immunotherapy has become an important part of the oncotherapy arsenal. Its applicability in various cancer types is impressive, as well as its use of endogenous mechanisms to achieve desired ends....
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Fobian S, Mei X, Crezee J, Snoek B, Steenbergen R, Hu J, et al.
J Med Virol . 2024 Jun; 96(6):e29741. PMID: 38922964
Cervical cancer is the fourth most common cancer in women worldwide and is caused by persistent infection with high-risk types of human papillomavirus (HPV). HPV viral load, the amount of...
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Fobian S, Petzer M, Vetten M, Steenkamp V, Gulumian M, Cordier W
J Pharm Pharmacol . 2022 Apr; 74(9):1282-1295. PMID: 35417021
Objectives: Nanomedicines represent theragnostic alternatives to traditional candidate drugs, with increased targeting and delivery potential due to their size and functional tailorability. Biological activity typically relies on nanomaterials permeating into...
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Fobian S, Cheng Z, Ten Hagen T
Pharmaceutics . 2022 Jan; 14(1). PMID: 35056922
Cancer immunotherapy, a promising and widely applied mode of oncotherapy, makes use of immune stimulants and modulators to overcome the immune dysregulation present in cancer, and leverage the host's immune...