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Seta Kupcu

Explore the profile of Seta Kupcu including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 282
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Recent Articles
1.
Zafiu C, Kupcu S, Kahkonen M
MethodsX . 2022 Nov; 9:101885. PMID: 36385913
Decolorization assays allow to assess the ability of white rot fungi to degrade persistent organic molecules such as textile dyes and can contribute to discover microorganisms that can be used...
2.
Eilenberger C, Rothbauer M, Brandauer K, Spitz S, Ehmoser E, Kupcu S, et al.
Pharmaceutics . 2022 Feb; 14(2). PMID: 35214071
Stem cell technology and embryonic stem cell models are of great interest in biomedical research since they provide deeper insights into, e.g., neurogenesis and early mammalian brain development. Despite their...
3.
Eilenberger C, Rothbauer M, Selinger F, Gerhartl A, Jordan C, Harasek M, et al.
Adv Sci (Weinh) . 2021 Jun; 8(11):e2004856. PMID: 34105271
Physiological-relevant in vitro tissue models with their promise of better predictability have the potential to improve drug screening outcomes in preclinical studies. Despite the advances of spheroid models in pharmaceutical...
4.
Rothbauer M, Holl G, Eilenberger C, Kratz S, Farooq B, Schuller P, et al.
Lab Chip . 2020 Mar; 20(8):1461-1471. PMID: 32219235
Rheumatoid arthritis is a chronic, systemic joint disease in which an autoimmune response translates into an inflammatory attack resulting in joint damage, disability and decreased quality of life. Despite recent...
5.
Eilenberger C, Rothbauer M, Ehmoser E, Ertl P, Kupcu S
Sci Rep . 2019 Mar; 9(1):4863. PMID: 30890741
The enhanced predictive power of 3D multi-cellular spheroids in comparison to conventional monolayer cultures makes them a promising drug screening tool. However, clinical translation for pharmacology and toxicology is lagging...
6.
Eilenberger C, Kratz S, Rothbauer M, Ehmoser E, Ertl P, Kupcu S
MethodsX . 2018 Aug; 5:781-787. PMID: 30094205
The assessment of drug-dose responses is vital for the prediction of unwanted toxicological effects in modern medicine. Three-dimensional (3D) cell cultures techniques can provide -like spheroids and microtissues that resemble...
7.
Eilenberger C, Rothbauer M, Ertl P, Kupcu S
Methods Mol Biol . 2018 Apr; 1771:251-258. PMID: 29633219
Several techniques have been established over the last decades to produce three-dimensional (3D) cellular spheroids and each method has its advantages and limitations. The unique self-assembly properties of surface layer...
8.
Rothbauer M, Frauenlob M, Gutkas K, Fischer M, Sinner E, Kupcu S, et al.
ACS Appl Mater Interfaces . 2017 Sep; 9(39):34423-34434. PMID: 28920671
We present a multifunctional nanobiointerface for blood cell capture and phenotyping applications that features both excellent antifouling properties and high antibody activity. Multifunctionality is accomplished by modifying polymeric materials using...
9.
Damiati S, Kupcu S, Peacock M, Eilenberger C, Zamzami M, Qadri I, et al.
Biosens Bioelectron . 2017 Mar; 94:500-506. PMID: 28343102
This study presents an efficient acoustic and hybrid three-dimensional (3D)-printed electrochemical biosensors for the detection of liver cancer cells. The biosensors function by recognizing the highly expressed tumor marker CD133,...
10.
Ucisik M, Kupcu S, Breitwieser A, Gelbmann N, Schuster B, Sleytr U
Colloids Surf B Biointerfaces . 2015 Mar; 128:132-139. PMID: 25734967
Selective targeting of tumor cells by nanoparticle-based drug delivery systems is highly desirable because it maximizes the drug concentration at the desired target while simultaneously protecting the surrounding healthy tissues....