Sergey Epshteyn
Overview
Explore the profile of Sergey Epshteyn including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
29
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0
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Recent Articles
1.
Takeuchi C, Kim B, Blazey C, Ma S, Johnson H, Anand N, et al.
J Med Chem
. 2013 Feb;
56(6):2218-34.
PMID: 23394126
A series of novel, highly potent, selective, and ATP-competitive mammalian target of rapamycin (mTOR) inhibitors based on a benzoxazepine scaffold have been identified. Lead optimization resulted in the discovery of...
2.
Forsyth T, Kearney P, Kim B, Johnson H, Aay N, Arcalas A, et al.
Bioorg Med Chem Lett
. 2012 Nov;
22(24):7653-8.
PMID: 23127890
We report the discovery of a series of 4-aryl-2-aminoalkylpyrimidine derivatives as potent and selective JAK2 inhibitors. High throughput screening of our in-house compound library led to the identification of hit...
3.
Folkes A, Brown S, Canne L, Chan J, Engelhardt E, Epshteyn S, et al.
Bioorg Med Chem Lett
. 2002 Mar;
12(7):1063-6.
PMID: 11909718
We have synthesized and evaluated a series of tetramic acid-based and hydroxyquinolinone-based inhibitors of plasminogen activator inhibitor-1 (PAI-1). These studies resulted in the identification of several compounds which showed excellent...