Seng H Liew
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Explore the profile of Seng H Liew including associated specialties, affiliations and a list of published articles.
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22
Citations
656
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Recent Articles
1.
Winship A, Alesi L, Sant S, Stringer J, Cantavenera A, Hegarty T, et al.
Nat Cancer
. 2022 Aug;
3(8):1-13.
PMID: 36008687
Loss of fertility is a major concern for female reproductive-age cancer survivors, since a common side-effect of conventional cytotoxic cancer therapies is permanent damage to the ovary. While immunotherapies are...
2.
Hutt K, Lim S, Zhang Q, Gonzalez M, OConnor A, Merriner D, et al.
Mol Hum Reprod
. 2021 Sep;
27(11).
PMID: 34590701
PIWI-interacting small RNAs (piRNAs) maintain genome stability in animal germ cells, with a predominant role in silencing transposable elements. Mutations in the piRNA pathway in the mouse uniformly lead to...
3.
Lliberos C, Liew S, Mansell A, Hutt K
Front Cell Dev Biol
. 2021 Mar;
8:628473.
PMID: 33644037
Ovarian aging is a natural process characterized by follicular depletion and a reduction in oocyte quality, resulting in loss of ovarian function, cycle irregularity and eventually infertility and menopause. The...
4.
Lliberos C, Liew S, Zareie P, La Gruta N, Mansell A, Hutt K
Sci Rep
. 2021 Jan;
11(1):278.
PMID: 33432051
Reproductive ageing in females is defined by a progressive decline in follicle number and oocyte quality. This is a natural process that leads to the loss of fertility and ovarian...
5.
McReight E, Liew S, Steane S, Hutt K, Moritz K, Akison L
Reproduction
. 2020 Mar;
159(5):615-626.
PMID: 32168471
Prenatal alcohol exposure (PAE) has been associated with reproductive dysfunction in offspring. However, studies in females, particularly examining long-term infertility or impacts on ovarian reserve, are lacking. The current study...
6.
Stringer J, Groenewegen E, Liew S, Hutt K
Reproduction
. 2019 Nov;
159(2):105-113.
PMID: 31751296
Primordial follicle oocytes are extremely vulnerable to DNA damage caused by exogenous agents, such as those commonly used to treat cancer. Consequently, female cancer patients often have diminished ovarian reserve,...
7.
Stringer J, Swindells E, Zerafa N, Liew S, Hutt K
Toxicol Sci
. 2018 Aug;
166(1):97-107.
PMID: 30085306
With increasing improvements in cancer survival rates, it is critical to reduce the significant long-term side effects that afflict patients following treatment. For women, consequences of chemotherapy-induced damage to the...
8.
Nguyen Q, Zerafa N, Liew S, Morgan F, Strasser A, Scott C, et al.
Cell Death Dis
. 2018 May;
9(6):618.
PMID: 29795269
Female gametes are stored in the ovary in structures called primordial follicles, the supply of which is non-renewable. It is well established that DNA-damaging cancer treatments can deplete the ovarian...
9.
Stringer J, Winship A, Liew S, Hutt K
Cell Mol Life Sci
. 2018 May;
75(15):2777-2792.
PMID: 29748894
Female fertility and offspring health are critically dependent on the maintenance of an adequate supply of high-quality oocytes. Like somatic cells, oocytes are subject to a variety of different types...
10.
Winship A, Bakai M, Sarma U, Liew S, Hutt K
Sci Rep
. 2018 Apr;
8(1):6516.
PMID: 29695822
Dacarbazine is commonly administered for the treatment of cancers prevalent in reproductive age females. However, investigations of off-target effects of dacarbazine on the ovary are limited. We assessed the impact...