Seisuke Yamashita
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Explore the profile of Seisuke Yamashita including associated specialties, affiliations and a list of published articles.
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19
Citations
382
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Recent Articles
1.
Yamashita S, Tomita K
Nucleic Acids Res
. 2025 Jan;
53(2).
PMID: 39831302
U6 snRNA (small nuclear ribonucleic acid) is a ribozyme that catalyzes pre-messenger RNA (pre-mRNA) splicing and undergoes epitranscriptomic modifications. After transcription, the 3'-end of U6 snRNA is oligo-uridylylated by the...
2.
Yamashita S, Tomita K
Nat Commun
. 2023 Aug;
14(1):4686.
PMID: 37563152
U6 snRNA is a catalytic RNA responsible for pre-mRNA splicing reactions and undergoes various post-transcriptional modifications during its maturation process. The 3'-oligouridylation of U6 snRNA by the terminal uridylyltransferase, TUT1,...
3.
Nagato Y, Yamashita S, Ohashi A, Furukawa H, Takai K, Tomita K, et al.
J Biochem
. 2023 Jun;
174(3):291-303.
PMID: 37261968
Glycyl-tRNA synthetases (GlyRSs) have different oligomeric structures depending on the organisms. While a dimeric α2 GlyRS species is present in archaea, eukaryotes and some eubacteria, a heterotetrameric α2β2 GlyRS species...
4.
Ju J, Aoyama T, Yashiro Y, Yamashita S, Kuroyanagi H, Tomita K
Nucleic Acids Res
. 2023 Feb;
51(5):2434-2446.
PMID: 36794723
In Caenorhabditis elegans, the N6-methyladenosine (m6A) modification by METT10, at the 3'-splice sites in S-adenosyl-l-methionine (SAM) synthetase (sams) precursor mRNA (pre-mRNA), inhibits sams pre-mRNA splicing, promotes alternative splicing coupled with...
5.
Ohira T, Minowa K, Sugiyama K, Yamashita S, Sakaguchi Y, Miyauchi K, et al.
Nature
. 2022 Apr;
605(7909):372-379.
PMID: 35477761
Post-transcriptional modifications have critical roles in tRNA stability and function. In thermophiles, tRNAs are heavily modified to maintain their thermal stability under extreme growth temperatures. Here we identified 2'-phosphouridine (U)...
6.
Aoyama T, Yamashita S, Tomita K
Nucleic Acids Res
. 2020 Apr;
48(9):5157-5168.
PMID: 32266935
The N6-methyladenosine modification at position 43 (m6A43) of U6 snRNA is catalyzed by METTL16, and is important for the 5'-splice site recognition by U6 snRNA during pre-mRNA splicing. Human METTL16...
7.
Liu Y, Martinez A, Yamashita S, Tomita K
Nucleic Acids Res
. 2020 Jan;
48(3):1572-1582.
PMID: 31919512
BCDIN3 domain containing RNA methyltransferase, BCDIN3D, monomethylates the 5'-monophosphate of cytoplasmic tRNAHis with a G-1:A73 mispair at the top of an eight-nucleotide-long acceptor helix, using S-adenosyl-l-methionine (SAM) as a methyl...
8.
Yamashita S, Nagaike T, Tomita K
Nat Commun
. 2019 May;
10(1):1960.
PMID: 31036859
Lin28-dependent oligo-uridylylation of precursor let-7 (pre-let-7) by terminal uridylyltransferase 4/7 (TUT4/7) represses let-7 expression by blocking Dicer processing, and regulates cell differentiation and proliferation. The interaction between the Lin28:pre-let-7 complex...
9.
Yashiro Y, Yamashita S, Tomita K
Structure
. 2019 Jan;
27(3):476-484.e3.
PMID: 30612860
AtaT-AtaR is an enterohemorrhagic Escherichia coli toxin-antitoxin system that modulates cellular growth under stress conditions. AtaT and AtaR act as a toxin and its repressor, respectively. AtaT is a member...
10.
Taniguchi T, Miyauchi K, Sakaguchi Y, Yamashita S, Soma A, Tomita K, et al.
Nat Chem Biol
. 2018 Aug;
14(11):1010-1020.
PMID: 30150682
Modification of tRNA anticodons plays a critical role in ensuring accurate translation. N-acetylcytidine (acC) is present at the anticodon first position (position 34) of bacterial elongator tRNA. Herein, we identified...