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Sebastien Viel

Explore the profile of Sebastien Viel including associated specialties, affiliations and a list of published articles. Areas
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Articles 70
Citations 2699
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Recent Articles
1.
Villard M, Viel S, Karlin L, Avet-Loiseau H, Martinet L, Marcais A, et al.
Eur J Immunol . 2025 Feb; 55(2):e202451191. PMID: 39931788
Multiple myeloma (MM) is a proliferation of tumoral plasma cells that is still incurable. Natural killer (NK) cells can recognize and kill MM cells in vitro. However, previous literature suggests...
2.
Guironnet-Paquet A, Hamzeh-Cognasse H, Berard F, Cognasse F, Richard J, Yonis H, et al.
Front Immunol . 2025 Feb; 15:1492672. PMID: 39896810
Background: Immunological disturbances (anti-type I IFN auto-antibody production, cytokine storm, lymphopenia, T-cell hyperactivation and exhaustion) are responsible for disease exacerbation during severe COVID-19 infections. Methods: In this study, we set...
3.
Boyer O, Bensoussan D, Bonig H, Chabannon C, Clemenceau B, Cuffel A, et al.
Bone Marrow Transplant . 2025 Jan; PMID: 39863732
The accessibility of CAR-T cells in centralized production models faces significant challenges, primarily stemming from logistical complexities and prohibitive costs. However, European Regulation EC No. 1394/2007 introduced a pivotal provision...
4.
Viel S, Vivier E, Walzer T, Marcais A
Nat Rev Drug Discov . 2024 Dec; 24(3):190-208. PMID: 39668206
The importance of metabolic pathways in regulating immune responses is now well established, and a mapping of the bioenergetic metabolism of different immune cell types is under way. CD8 T...
5.
Gauthier L, Gossez M, Malcus C, Viel S, Monneret G, Bordonne R, et al.
Clin Genet . 2024 Jun; 106(4):476-482. PMID: 38837402
Microcephalic osteodysplastic primordial dwarfism type I (MOPDI) is a very rare and severe autosomal recessive disorder characterized by marked intrauterine growth retardation, skeletal dysplasia, microcephaly and brain malformations. MOPDI is...
6.
Solignac M, Cabrera N, Fouillet-Desjonqueres M, Duquesne A, Laurent A, Foray A, et al.
J Autoimmun . 2024 May; 147:103248. PMID: 38797048
Objectives: - Janus Kinase inhibitors (JAKi) are a new class of drugs available for pediatric rheumatic diseases. This study aimed to describe the safety and effectiveness of JAKi in these...
7.
Tusseau M, Khaldi-Plassart S, Cognard J, Viel S, Khoryati L, Benezech S, et al.
J Clin Immunol . 2024 Apr; 44(4):99. PMID: 38619739
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterized by its large heterogeneity in terms of clinical presentation and severity. The pathophysiology of SLE involves an aberrant...
8.
Belot A, Rice G, Omarjee S, Rouchon Q, Smith E, Moreews M, et al.
Lancet Rheumatol . 2024 Jan; 2(2):e99-e109. PMID: 38263665
Background: Systemic lupus erythematosus (SLE) is a rare immunological disorder and genetic factors are considered important in its causation. Monogenic lupus has been associated with around 30 genotypes in humans...
9.
Pavel-Dinu M, Gardner C, Nakauchi Y, Kawai T, Delmonte O, Palterer B, et al.
Blood Adv . 2023 Dec; 8(7):1820-1833. PMID: 38096800
Recombination-activating genes (RAG1 and RAG2) are critical for lymphoid cell development and function by initiating the variable (V), diversity (D), and joining (J) (V(D)J)-recombination process to generate polyclonal lymphocytes with...
10.
Benezech S, Khoryati L, Cognard J, Netea S, Khan T, Moreews M, et al.
N Engl J Med . 2023 Dec; 389(22):2105-2107. PMID: 38048195
No abstract available.