Sebastien Plancon
Overview
Explore the profile of Sebastien Plancon including associated specialties, affiliations and a list of published articles.
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10
Citations
188
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Recent Articles
1.
Zhou Y, Hann J, Schenten V, Plancon S, Bueb J, Tolle F, et al.
Int J Mol Sci
. 2021 Aug;
22(16).
PMID: 34445548
S100A9, a Ca-binding protein, is tightly associated to neutrophil pro-inflammatory functions when forming a heterodimer with its S100A8 partner. Upon secretion into the extracellular environment, these proteins behave like damage-associated...
2.
Schenten V, Plancon S, Jung N, Hann J, Bueb J, Brechard S, et al.
Front Immunol
. 2018 Mar;
9:447.
PMID: 29593718
S100A8 and S100A9 are members of the S100 family of cytoplasmic EF-hand Ca-binding proteins and are abundantly expressed in the cytosol of neutrophils. In addition to their intracellular roles, S100A8/A9...
3.
Naegelen I, Beaume N, Plancon S, Schenten V, Tschirhart E, Brechard S
J Immunol Res
. 2015 Nov;
2015:817038.
PMID: 26579547
Neutrophils participate in the maintenance of host integrity by releasing various cytotoxic proteins during degranulation. Due to recent advances, a major role has been attributed to neutrophil-derived cytokine secretion in...
4.
Naegelen I, Plancon S, Nicot N, Kaoma T, Muller A, Vallar L, et al.
J Leukoc Biol
. 2014 Dec;
97(3):557-71.
PMID: 25548252
Besides their roles in the killing of pathogens, neutrophils have the capacity to package a variety of cytokines into cytoplasmic granules for subsequent release upon inflammatory conditions. Because the rapid...
5.
Brechard S, Plancon S, Tschirhart E
Antioxid Redox Signal
. 2012 Aug;
18(6):661-76.
PMID: 22867131
Significance: Reactive oxygen species, produced by the phagosomal NADPH oxidase of neutrophils, play a significant physiological role during normal defense. Their role is not only to kill invading pathogens, but...
6.
Schenten V, Brechard S, Plancon S, Melchior C, Frippiat J, Tschirhart E
Biochim Biophys Acta
. 2010 Mar;
1803(7):840-7.
PMID: 20219570
The neutrophil NADPH oxidase (NOX2) is a key enzyme responsible for host defense against invading pathogens, via the production of reactive oxygen species. Dysfunction of NOX2 can contribute to inflammatory...
7.
Vanhoorelbeke K, De Meyer S, Pareyn I, Melchior C, Plancon S, Margue C, et al.
J Biol Chem
. 2009 Mar;
284(22):14914-20.
PMID: 19329429
Three heterozygous mutations were identified in the genes encoding platelet integrin receptor alphaIIbbeta3 in a patient with an ill defined platelet disorder: one in the beta3 gene (S527F) and two...
8.
Salsmann A, Schaffner-Reckinger E, Kabile F, Plancon S, Kieffer N
J Biol Chem
. 2005 Jun;
280(39):33610-9.
PMID: 15955823
A number of RGD-type integrins rely on a synergistic site in addition to the canonical RGD site for ligand binding and signaling, although it is still unclear whether these two...
9.
Kieffer N, Schmitz M, Plancon S, Margue C, Huselstein F, Grignard G, et al.
Int J Oncol
. 2005 May;
26(6):1549-58.
PMID: 15870868
A major technical challenge related to gene expression profiling of tissue samples is the difficulty of procuring selected cell populations from tissues that by nature are heterogeneous, such as prostate...
10.
Tremuth L, Kreis S, Melchior C, Hoebeke J, Ronde P, Plancon S, et al.
J Biol Chem
. 2004 Mar;
279(21):22258-66.
PMID: 15031296
The cytoskeletal protein talin, which provides a direct link between integrins and actin filaments, has been shown to contain two distinct binding sites for integrin beta subunits. Here, we report...