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Sebastien Jacques

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Articles 52
Citations 864
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Recent Articles
1.
Beaumont H, Iannessi A, Thinnes A, Jacques S, Quintas-Cardama A
Cancers (Basel) . 2025 Feb; 17(3). PMID: 39941830
Background/objectives: T cell receptor fusion constructs (TRuCs), a next generation engineered T cell therapy, hold great promise. To accelerate the clinical development of these therapies, improving patient selection is a...
2.
Felfli M, Thinnes A, Jacques S, Liu Y, Iannessi A
Front Immunol . 2025 Jan; 15:1470555. PMID: 39759519
Objective: Assess the contribution of early tumor growth dynamics modeling to predict clinical outcomes in non-small cell lung cancer patients receiving immunotherapy, alongside standard RECIST 1.1 criteria. Methods: Our retrospective...
3.
Miladinovic O, Canto P, Pouget C, Piau O, Radic N, Freschu P, et al.
Development . 2024 Mar; 151(7). PMID: 38451068
The first hematopoietic stem and progenitor cells (HSPCs) emerge in the Aorta-Gonad-Mesonephros (AGM) region of the mid-gestation mouse embryo. However, the precise nature of their supportive mesenchymal microenvironment remains largely...
4.
Durand A, Bonilla N, Level T, Ginestet Z, Lombes A, Guichard V, et al.
Nat Commun . 2024 Feb; 15(1):1718. PMID: 38409097
Foxo family transcription factors are critically involved in multiple processes, such as metabolism, quiescence, cell survival and cell differentiation. Although continuous, high activity of Foxo transcription factors extends the life...
5.
Felfli M, Liu Y, Zerka F, Voyton C, Thinnes A, Jacques S, et al.
Int J Mol Sci . 2023 Jul; 24(14). PMID: 37511192
Assessment of the quality and current performance of computed tomography (CT) radiomics-based models in predicting epidermal growth factor receptor (EGFR) mutation status in patients with non-small-cell lung carcinoma (NSCLC). Two...
6.
Kouakou F, Denizot A, LHostis A, Colet J, Jacques S, Sallem A, et al.
EBioMedicine . 2023 Apr; 91:104572. PMID: 37094466
Background: The exposure to plastic derivatives during human life is deleterious. Infants conceived using ART (IVF or ICSI) have twice as many risks of major birth defects compared to naturally...
7.
Apicella C, Ruano C, Thilaganathan B, Khalil A, Giorgione V, Gascoin G, et al.
Cells . 2023 Feb; 12(4). PMID: 36831244
In this study, we attempted to find genetic variants affecting gene expression (eQTL = expression Quantitative Trait Loci) in the human placenta in normal and pathological situations. The analysis of...
8.
Barret M, Doridot L, Le Gall M, Beuvon F, Jacques S, Pellat A, et al.
Endosc Int Open . 2023 Feb; 11(2):E149-E156. PMID: 36741340
Esophageal stricture is the most frequent adverse event after endoscopic resection for early esophageal neoplasia. Currently available treatments for the prevention of esophageal stricture are poorly effective and associated with...
9.
Pacot L, Chansavang A, Jacques S, Laurendeau I, Hadjadj D, Ferkal S, et al.
Eur J Hum Genet . 2023 Feb; 31(4):380-382. PMID: 36732663
No abstract available.
10.
Leuillier M, Duflot T, Menoret S, Messaoudi H, Djerada Z, Groussard D, et al.
J Adv Res . 2022 Dec; 43:163-174. PMID: 36585106
Introduction: Although the physiological role of the C-terminal hydrolase domain of the soluble epoxide hydrolase (sEH-H) is well investigated, the function of its N-terminal phosphatase activity (sEH-P) remains unknown. Objectives:...