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Sebastien Herbert

Explore the profile of Sebastien Herbert including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 323
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Recent Articles
1.
Mancini L, Guirao B, Ortica S, Labusch M, Cheysson F, Bonnet V, et al.
Sci Adv . 2023 Sep; 9(35):eadg7519. PMID: 37656795
The maintenance of neural stem cells (NSCs) in the adult brain depends on their activation frequency and division mode. Using long-term intravital imaging of NSCs in the zebrafish adult telencephalon,...
2.
Herbert S, Valon L, Mancini L, Dray N, Caldarelli P, Gros J, et al.
BMC Biol . 2021 Jul; 19(1):136. PMID: 34215263
Background: Quantitative imaging of epithelial tissues requires bioimage analysis tools that are widely applicable and accurate. In the case of imaging 3D tissues, a common preprocessing step consists of projecting...
3.
Dray N, Mancini L, Binshtok U, Cheysson F, Supatto W, Mahou P, et al.
Cell Stem Cell . 2021 Apr; 28(8):1457-1472.e12. PMID: 33823144
Neural stem cell (NSC) populations persist in the adult vertebrate brain over a lifetime, and their homeostasis is controlled at the population level through unknown mechanisms. Here, we combine dynamic...
4.
Kaufmann T, Herbert S, Hackl B, Besold J, Schramek C, Gotzmann J, et al.
Nucleic Acids Res . 2020 Oct; 48(21):e122. PMID: 33053171
Protein-protein interactions are essential to ensure timely and precise recruitment of chromatin remodellers and repair factors to DNA damage sites. Conventional analyses of protein-protein interactions at a population level may...
5.
Garbrecht J, Hornegger H, Herbert S, Kaufmann T, Gotzmann J, Elsayad K, et al.
Nucleus . 2018 Sep; 9(1):474-491. PMID: 30205747
Fluorescence microscopy in combination with the induction of localized DNA damage using focused light beams has played a major role in the study of protein recruitment kinetics to DNA damage...
6.
Lancino M, Majello S, Herbert S, de Chaumont F, Tinevez J, Olivo-Marin J, et al.
Elife . 2018 Aug; 7. PMID: 30132756
Hematopoiesis leads to the formation of blood and immune cells. Hematopoietic stem cells emerge during development, from vascular components, via a process called the endothelial-to-hematopoietic transition (EHT). Here, we reveal...
7.
Kaufmann T, Grishkovskaya I, Polyansky A, Kostrhon S, Kukolj E, Olek K, et al.
Nucleic Acids Res . 2017 Sep; 45(16):9741-9759. PMID: 28934471
Poly(ADP-ribose) glycohydrolase (PARG) regulates cellular poly(ADP-ribose) (PAR) levels by rapidly cleaving glycosidic bonds between ADP-ribose units. PARG interacts with proliferating cell nuclear antigen (PCNA) and is strongly recruited to DNA...
8.
Herbert S, Brion A, Arbona J, Lelek M, Veillet A, Lelandais B, et al.
EMBO J . 2017 Jul; 36(17):2595-2608. PMID: 28694242
DNA double-strand breaks (DSBs) induce a cellular response that involves histone modifications and chromatin remodeling at the damaged site and increases chromosome dynamics both locally at the damaged site and...
9.
Arbona J, Herbert S, Fabre E, Zimmer C
Genome Biol . 2017 May; 18(1):81. PMID: 28468672
Background: The structure and mechanical properties of chromatin impact DNA functions and nuclear architecture but remain poorly understood. In budding yeast, a simple polymer model with minimal sequence-specific constraints and...
10.
Spichal M, Brion A, Herbert S, Cournac A, Marbouty M, Zimmer C, et al.
J Cell Sci . 2016 Jan; 129(4):681-92. PMID: 26763908
Eukaryotic chromosomes undergo movements that are involved in the regulation of functional processes such as DNA repair. To better understand the origin of these movements, we used fluorescence microscopy, image...