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Sebastian Vlaic

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Articles 17
Citations 197
Followers 0
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Recent Articles
1.
Arlt J, Vlaic S, Feuer R, Thomas M, Settmacher U, Dahmen U, et al.
BMC Med Genomics . 2022 Oct; 15(1):211. PMID: 36207717
Background: In previous studies, five vasoactive drugs were investigated for their effect on the recovery process after extended liver resection without observing relevant improvements. We hypothesized that an analysis of...
2.
Nickel S, Vlaic S, Christ M, Schubert K, Henschler R, Tautenhahn F, et al.
NPJ Regen Med . 2021 Dec; 6(1):84. PMID: 34862411
Post-surgery liver failure is a serious complication for patients after extended partial hepatectomies (ePHx). Previously, we demonstrated in the pig model that transplantation of mesenchymal stromal cells (MSC) improved circulatory...
3.
Kaur S, Rawal P, Siddiqui H, Rohilla S, Sharma S, Tripathi D, et al.
Cells . 2019 Oct; 8(10). PMID: 31635436
Given the important role of angiogenesis in liver pathology, the current study investigated the role of Runt-related transcription factor 1 (RUNX1), a regulator of developmental angiogenesis, in the pathogenesis of...
4.
Rennert C, Vlaic S, Marbach-Breitruck E, Thiel C, Sales S, Shevchenko A, et al.
Front Physiol . 2018 Oct; 9:1180. PMID: 30271348
Organisms adapt their metabolism and draw on reserves as a consequence of food deprivation. The central role of the liver in starvation response is to coordinate a sufficient energy supply...
5.
Schaarschmidt B, Vlaic S, Medyukhina A, Neugebauer S, Nietzsche S, Gonnert F, et al.
Theranostics . 2018 Aug; 8(14):3766-3780. PMID: 30083258
The liver is a central organ not only for metabolism but also immune function. Life-threatening infections of both bacterial and fungal origin can affect liver function but it is yet...
6.
Schmidt H, Vlaic S, Kruger T, Schmidt F, Balkenhol J, Dandekar T, et al.
Mol Cell Proteomics . 2018 Mar; 17(6):1084-1096. PMID: 29507050
Invasive infections by the human pathogenic fungus start with the outgrowth of asexual, airborne spores (conidia) into the lung tissue of immunocompromised patients. The resident alveolar macrophages phagocytose conidia, which...
7.
Vlaic S, Conrad T, Tokarski-Schnelle C, Gustafsson M, Dahmen U, Guthke R, et al.
Sci Rep . 2018 Jan; 8(1):433. PMID: 29323246
The identification of disease-associated modules based on protein-protein interaction networks (PPINs) and gene expression data has provided new insights into the mechanistic nature of diverse diseases. However, their identification is...
8.
Christ B, Dahmen U, Herrmann K, Konig M, Reichenbach J, Ricken T, et al.
Front Physiol . 2017 Dec; 8:906. PMID: 29249974
The need for extended liver resection is increasing due to the growing incidence of liver tumors in aging societies. Individualized surgical planning is the key for identifying the optimal resection...
9.
Hebecker B, Vlaic S, Conrad T, Bauer M, Brunke S, Kapitan M, et al.
Sci Rep . 2016 Dec; 6:39423. PMID: 27991566
No abstract available.
10.
Hebecker B, Vlaic S, Conrad T, Bauer M, Brunke S, Kapitan M, et al.
Sci Rep . 2016 Nov; 6:36055. PMID: 27808111
Candida albicans is a common cause of life-threatening fungal bloodstream infections. In the murine model of systemic candidiasis, the kidney is the primary target organ while the fungal load declines...