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Sebastian Thams

Explore the profile of Sebastian Thams including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 1217
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Recent Articles
1.
Bellotti C, Samudyata S, Thams S, Sellgren C, Rostami E
Acta Neuropathol Commun . 2024 Aug; 12(1):141. PMID: 39215375
Research in the field of traumatic brain injury has until now heavily relied on the use of animal models to identify potential therapeutic approaches. However, a long series of failed...
2.
Lindblad C, Neumann S, Kolbeinsdottir S, Zachariadis V, Thelin E, Enge M, et al.
J Inflamm (Lond) . 2023 Jun; 20(1):22. PMID: 37370141
Background: Astrocytes respond to injury and disease through a process known as reactive astrogliosis, of which inflammatory signaling is one subset. This inflammatory response is heterogeneous with respect to the...
3.
Sennfalt S, Klappe U, Thams S, Samuelsson K, Press R, Fang F, et al.
Amyotroph Lateral Scler Frontotemporal Degener . 2022 Jul; 24(3-4):237-245. PMID: 35818691
Objectives: This retrospective cohort study aims to provide a comprehensive account of death in Swedish patients with ALS, including clinical status preceding death, the death setting, as well as symptoms....
4.
Sennfalt S, Klappe U, Thams S, Samuelsson K, Press R, Fang F, et al.
Amyotroph Lateral Scler Frontotemporal Degener . 2022 Mar; 24(1-2):45-53. PMID: 35343340
: To provide a detailed and differentiated description of the path to receiving the correct amyotrophic lateral sclerosis (ALS) diagnosis, including delay times, referrals, alternate diagnoses, and clinical progression.: Medical...
5.
Thams S, Paucar M, Wingard L, Thonberg H, Smith C, Nennesmo I, et al.
Neurol Genet . 2021 Nov; 7(6):e636. PMID: 34746379
No abstract available.
6.
Gustafsson D, Klang A, Thams S, Rostami E
Int J Mol Sci . 2021 Apr; 22(7). PMID: 33808272
Traumatic brain injury is one of the leading causes of mortality and morbidity in the world with no current pharmacological treatment. The role of BDNF in neural repair and regeneration...
7.
Foo K, Lehtinen M, Leung C, Lian X, Xu J, Keung W, et al.
Mol Ther . 2020 Dec; 29(1):409. PMID: 33296664
No abstract available.
8.
Thams S, Islam M, Lindefeldt M, Nordgren A, Granberg T, Tesi B, et al.
Neurol Genet . 2020 Nov; 6(6):e526. PMID: 33209984
Objective: To perform a comprehensive characterization of a cohort of patients with congenital mirror movements (CMMs) in Sweden. Methods: Clinical examination with the Woods and Teuber scale for mirror movements...
9.
Bos P, Lowry E, Costa J, Thams S, Garcia-Diaz A, Zask A, et al.
Cell Chem Biol . 2019 Nov; 26(12):1703-1715.e37. PMID: 31676236
Disease-causing mutations in many neurodegenerative disorders lead to proteinopathies that trigger endoplasmic reticulum (ER) stress. However, few therapeutic options exist for patients with these diseases. Using an in vitro screening...
10.
Tung Y, Peng K, Chen Y, Yen Y, Chang M, Thams S, et al.
Cell Stem Cell . 2019 Jun; 25(2):193-209.e7. PMID: 31155482
Progressive degeneration of motor neurons (MNs) is the hallmark of amyotrophic lateral sclerosis (ALS). Limb-innervating lateral motor column MNs (LMC-MNs) seem to be particularly vulnerable and are among the first...