Sebastian R Merker
Overview
Explore the profile of Sebastian R Merker including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
302
Followers
0
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Recent Articles
1.
Wong F, Merker S, Bauer L, Han Y, Le V, Wenzel C, et al.
Br J Cancer
. 2025 Jan;
132(4):326-339.
PMID: 39863771
Background: Pancreatic ductal adenocarcinoma (PDAC) exhibits a high frequency of neural invasion (NI). Schwann cells (SCs) have been shown to be reprogrammed to facilitate cancer cell migration and invasion into...
2.
Pape K, Lossner A, William D, Czempiel T, Beyreuther E, Klimova A, et al.
Cancers (Basel)
. 2022 Oct;
14(20).
PMID: 36291768
Pathological complete response (pCR) has been correlated with overall survival in several cancer entities including colorectal cancer. Novel total neoadjuvant treatment (TNT) in rectal cancer has achieved pathological complete response...
3.
Seidlitz T, Chen Y, Uhlemann H, Scholch S, Kochall S, Merker S, et al.
Gastroenterology
. 2019 Oct;
157(6):1599-1614.e2.
PMID: 31585123
Background & Aims: Patterns of genetic alterations characterize different molecular subtypes of human gastric cancer. We aimed to establish mouse models of these subtypes. Methods: We searched databases to identify...
4.
Han S, Fink J, Jorg D, Lee E, Yum M, Chatzeli L, et al.
Cell Stem Cell
. 2019 Aug;
25(3):342-356.e7.
PMID: 31422913
The gastric corpus epithelium is the thickest part of the gastrointestinal tract and is rapidly turned over. Several markers have been proposed for gastric corpus stem cells in both isthmus...
5.
Seidlitz T, Merker S, Rothe A, Zakrzewski F, von Neubeck C, Grutzmann K, et al.
Gut
. 2018 Apr;
68(2):207-217.
PMID: 29703791
Objective: Gastric cancer is the second leading cause of cancer-related deaths and the fifth most common malignancy worldwide. In this study, human and mouse gastric cancer organoids were generated to...
6.
Kurlishchuk Y, Vynnytska-Myronovska B, Grosse-Gehling P, Bobak Y, Manig F, Chen O, et al.
Oncotarget
. 2016 Oct;
7(45):73292-73308.
PMID: 27689335
The moderate anticancer effect of arginine deprivation in clinical trials has been linked to an induced argininosuccinate synthetase (ASS1) expression in initially ASS1-negative tumors, and ASS1-positive cancers are anticipated as...
7.
Merker S, Weitz J, Stange D
Dev Biol
. 2016 Aug;
420(2):239-250.
PMID: 27521455
The gastrointestinal tract is characterized by a self-renewing epithelium fueled by adult stem cells residing at the bottom of the intestinal crypt and gastric glands. Their activity and proliferation is...