Daniel E Stange
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Explore the profile of Daniel E Stange including associated specialties, affiliations and a list of published articles.
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57
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12769
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Recent Articles
1.
Teske C, Liedel K, Hirle A, Baenke F, Stange D, Weitz J, et al.
Cancer Med
. 2024 Dec;
13(23):e70457.
PMID: 39632477
Background: Pancreatic ductal adenocarcinoma (PDAC) continues to pose profound challenges within the field of oncology due to its notorious resistance to existing therapies and constant high mortality rates. The recent...
2.
Schmache T, Fohgrub J, Klimova A, Laaber K, Drukewitz S, Merboth F, et al.
Mol Cancer
. 2024 Jan;
23(1):10.
PMID: 38200602
Background And Aims: This study sought to determine the value of patient-derived organoids (PDOs) from esophago-gastric adenocarcinoma (EGC) for response prediction to neoadjuvant chemotherapy (neoCTx). Methods: Endoscopic biopsies of patients...
3.
Muti H, Rocken C, Behrens H, Loffler C, Reitsam N, Grosser B, et al.
Eur J Cancer
. 2023 Oct;
194:113335.
PMID: 37862795
Aim: Gastric cancer (GC) is a tumour entity with highly variant outcomes. Lymph node metastasis is a prognostically adverse biomarker. We hypothesised that GC primary tissue contains information that is...
4.
Bandzeviciute R, Steiner G, Liedel K, Golde J, Koch E, Welsch T, et al.
J Biomed Opt
. 2023 May;
28(4):045004.
PMID: 37122477
Significance: Pancreatic surgery is a highly demanding and routinely applied procedure for the treatment of several pancreatic lesions. The outcome of patients with malignant entities crucially depends on the margin...
5.
Mircetic J, Camgoz A, Abohawya M, Ding L, Dietzel J, Tobar S, et al.
Small Methods
. 2023 Mar;
7(6):e2201605.
PMID: 36908010
Viability CRISPR screens have proven indispensable in parsing genome function. However, their application in new, more physiologically relevant culturing systems like patient-derived organoids (PDOs) has been much slower. To probe...
6.
Kast V, Nadernezhad A, Pette D, Gabrielyan A, Fusenig M, Honselmann K, et al.
Adv Healthc Mater
. 2022 Nov;
12(14):e2201907.
PMID: 36417691
Pancreatic cancer is a devastating malignancy with minimal treatment options. Standard-of-care therapy, including surgery and chemotherapy, is unsatisfactory, and therapies harnessing the immune system have been unsuccessful in clinical trials....
7.
Merboth F, Nebelung H, Wotschel N, Liebscher H, Eckert F, von Renesse J, et al.
J Thorac Oncol
. 2022 Nov;
18(2):232-244.
PMID: 36343921
Introduction: Sarcopenia is a known risk factor for adverse outcomes after esophageal cancer (EC) surgery. Robot-assisted minimally invasive esophagectomy (RAMIE) offers numerous advantages, including reduced morbidity and mortality. However, no...
8.
Pape K, Lossner A, William D, Czempiel T, Beyreuther E, Klimova A, et al.
Cancers (Basel)
. 2022 Oct;
14(20).
PMID: 36291768
Pathological complete response (pCR) has been correlated with overall survival in several cancer entities including colorectal cancer. Novel total neoadjuvant treatment (TNT) in rectal cancer has achieved pathological complete response...
9.
Sensitivity towards HDAC inhibition is associated with RTK/MAPK pathway activation in gastric cancer
Seidlitz T, Schmache T, Garcia F, Lee J, Qin N, Kochall S, et al.
EMBO Mol Med
. 2022 Aug;
14(10):e15705.
PMID: 35993110
Gastric cancer ranks the fifth most common and third leading cause of cancer-related deaths worldwide. Alterations in the RTK/MAPK, WNT, cell adhesion, TP53, TGFβ, NOTCH, and NFκB signaling pathways could...
10.
Naumann M, Czempiel T, Lossner A, Pape K, Beyreuther E, Lock S, et al.
Cancers (Basel)
. 2022 Aug;
14(15).
PMID: 35954444
To optimize neoadjuvant radiochemotherapy of pancreatic ductal adenocarcinoma (PDAC), the value of new irradiation modalities such as proton therapy needs to be investigated in relevant preclinical models. We studied individual...