Sebastian N W Hoernstein
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Explore the profile of Sebastian N W Hoernstein including associated specialties, affiliations and a list of published articles.
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21
Citations
377
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Recent Articles
11.
Top O, Parsons J, Bohlender L, Michelfelder S, Kopp P, Busch-Steenberg C, et al.
Front Plant Sci
. 2019 Apr;
10:260.
PMID: 30949184
The human complement system is an important part of the immune system responsible for lysis and elimination of invading microorganisms and apoptotic body cells. Improper activation of the system due...
12.
Hoernstein S, Fode B, Wiedemann G, Lang D, Niederkruger H, Berg B, et al.
J Proteome Res
. 2018 Sep;
17(11):3749-3760.
PMID: 30226384
Host cell proteins are inevitable contaminants of biopharmaceuticals. Here, we performed detailed analyses of the host cell proteome of moss ( Physcomitrella patens) bioreactor supernatants using mass spectrometry and subsequent...
13.
Toplak M, Wiedemann G, Ulicevic J, Daniel B, Hoernstein S, Kothe J, et al.
FEBS J
. 2018 Apr;
285(10):1923-1943.
PMID: 29633551
Database: Structural data are available in the PDB under the accession numbers 6EO4 and 6EO5.
14.
Lang D, Ullrich K, Murat F, Fuchs J, Jenkins J, Haas F, et al.
Plant J
. 2017 Dec;
93(3):515-533.
PMID: 29237241
The draft genome of the moss model, Physcomitrella patens, comprised approximately 2000 unordered scaffolds. In order to enable analyses of genome structure and evolution we generated a chromosome-scale genome assembly...
15.
Michelfelder S, Parsons J, Bohlender L, Hoernstein S, Niederkruger H, Busch A, et al.
J Am Soc Nephrol
. 2016 Dec;
28(5):1462-1474.
PMID: 27932477
Genetic defects in complement regulatory proteins can lead to severe renal diseases, including atypical hemolytic uremic syndrome and C3 glomerulopathies, and age-related macular degeneration. The majority of the mutations found...
16.
Mueller S, Hoernstein S, Reski R
Methods Mol Biol
. 2016 Oct;
1511:13-28.
PMID: 27730599
The function of subcellular structures is defined by their specific sets of proteins, making subcellular protein localization one of the most important topics in organelle research. To date, many organelle...
17.
Mueller S, Hoernstein S, Reski R
Mitochondrion
. 2016 Jul;
33:38-44.
PMID: 27450107
Extant basal land plants are routinely used to trace plant evolution and to track strategies for high abiotic stress resistance. Whereas the structure of mitochondrial genomes and RNA editing are...
18.
Hoernstein S, Mueller S, Fiedler K, Schuelke M, Vanselow J, Schuessele C, et al.
Mol Cell Proteomics
. 2016 Apr;
15(6):1808-22.
PMID: 27067052
Protein arginylation is a posttranslational modification of both N-terminal amino acids of proteins and sidechain carboxylates and can be crucial for viability and physiology in higher eukaryotes. The lack of...
19.
Schuessele C, Hoernstein S, Mueller S, Rodriguez-Franco M, Lorenz T, Lang D, et al.
New Phytol
. 2015 Oct;
209(3):1014-27.
PMID: 26428055
The importance of the arginyl-tRNA protein transferase (ATE), the enzyme mediating post-translation arginylation of proteins in the N-end rule degradation (NERD) pathway of protein stability, was analysed in Physcomitrella patens...
20.
Mueller S, Lang D, Hoernstein S, Lang E, Schuessele C, Schmidt A, et al.
Plant Physiol
. 2014 Feb;
164(4):2081-95.
PMID: 24515833
Extant eukaryotes are highly compartmentalized and have integrated endosymbionts as organelles, namely mitochondria and plastids in plants. During evolution, organellar proteomes are modified by gene gain and loss, by gene...