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Sebastian Klug

Explore the profile of Sebastian Klug including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 41
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Recent Articles
1.
Kirchner A, Espenhahn T, Klug S, Nielsch K, Huhne R
Materials (Basel) . 2024 Sep; 17(18). PMID: 39336257
Bulk high-temperature superconductors (HTSs) such as BaCuO (BCO, = Y, Gd) are commonly used in rotationally symmetric superconducting magnetic bearings. However, such bulks have several disadvantages such as brittleness, limited...
2.
Hahn A, Reed M, Murgas M, Vraka C, Klug S, Schmidt C, et al.
Mol Psychiatry . 2024 Aug; 30(2):600-607. PMID: 39179904
Serotonin (5-HT) plays an essential role in reward processing, however, the possibilities to investigate 5-HT action in humans during emotional stimulation are particularly limited. Here we demonstrate the feasibility of...
3.
Klug S, Murgas M, Godbersen G, Hacker M, Lanzenberger R, Hahn A
Neuroimage . 2024 May; 295:120658. PMID: 38810891
Purpose: The human brain is characterized by interacting large-scale functional networks fueled by glucose metabolism. Since former studies could not sufficiently clarify how these functional connections shape glucose metabolism, we...
4.
Reed M, Handschuh P, Schmidt C, Murgas M, Gomola D, Milz C, et al.
Eur J Nucl Med Mol Imaging . 2024 Apr; 51(9):2625-2637. PMID: 38676734
Purpose: Functional PET (fPET) is a novel technique for studying dynamic changes in brain metabolism and neurotransmitter signaling. Accurate quantification of fPET relies on measuring the arterial input function (AIF),...
5.
Godbersen G, Falb P, Klug S, Silberbauer L, Reed M, Nics L, et al.
Eur J Nucl Med Mol Imaging . 2024 Mar; 51(8):2283-2292. PMID: 38491215
Purpose: Functional positron emission tomography (fPET) with [F]FDG allows quantification of stimulation-induced changes in glucose metabolism independent of neurovascular coupling. However, the gold standard for quantification requires invasive arterial blood...
6.
Hahn A, Reed M, Vraka C, Godbersen G, Klug S, Komorowski A, et al.
Eur J Nucl Med Mol Imaging . 2023 Dec; 51(5):1310-1322. PMID: 38052927
Purpose: Positron emission tomography (PET) provides precise molecular information on physiological processes, but its low temporal resolution is a major obstacle. Consequently, we characterized the metabolic response of the human...
7.
Spagnolo A, Klug S, Schenkl C, Schwarzer M
Compr Physiol . 2023 Sep; 13(4):5115-5155. PMID: 37770189
Exercise capacity of an individual describes the ability to perform physical activity. This exercise capacity is influenced by intrinsic factors such as genetic constitution and extrinsic factors such as exercise...
8.
Godbersen G, Klug S, Wadsak W, Pichler V, Raitanen J, Rieckmann A, et al.
Elife . 2023 May; 12. PMID: 37226880
External tasks evoke characteristic fMRI BOLD signal deactivations in the default mode network (DMN). However, for the corresponding metabolic glucose demands both decreases and increases have been reported. To resolve...
9.
Reed M, Ponce de Leon M, Vraka C, Rausch I, Godbersen G, Popper V, et al.
Neuroimage . 2023 Mar; 271:120030. PMID: 36925087
The nervous and circulatory system interconnects the various organs of the human body, building hierarchically organized subsystems, enabling fine-tuned, metabolically expensive brain-body and inter-organ crosstalk to appropriately adapt to internal...
10.
Klug S, Godbersen G, Rischka L, Wadsak W, Pichler V, Klobl M, et al.
Commun Biol . 2022 May; 5(1):428. PMID: 35534605
The neurobiological basis of learning is reflected in adaptations of brain structure, network organization and energy metabolism. However, it is still unknown how different neuroplastic mechanisms act together and if...