Sebastian E Koschade
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Explore the profile of Sebastian E Koschade including associated specialties, affiliations and a list of published articles.
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20
Citations
178
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Recent Articles
1.
Moser L, Heim C, Koschade S, Wendel P, Bozkurt S, Harenkamp S, et al.
Front Immunol
. 2025 Feb;
16:1485817.
PMID: 39963129
Introduction: CAR-T cell therapy, though successful in hematologic malignancies, faces challenges in solid tumors due to limitations of autologous T cells. Cytokine-induced killer (CIK) cells can be given safely across...
2.
Seibert M, Koschade S, Stolp V, Haupl B, Wempe F, Serve H, et al.
Cancers (Basel)
. 2023 Dec;
15(23).
PMID: 38067212
Multiple myeloma (MM) is a malignant plasma cell disorder in which the MYC oncogene is frequently dysregulated. Due to its central role, MYC has been proposed as a drug target;...
3.
Mende H, Khatri A, Lange C, Poveda-Cuevas S, Tascher G, Covarrubias-Pinto A, et al.
Cell Rep
. 2023 Nov;
42(12):113484.
PMID: 37999976
The nucleolar scaffold protein NPM1 is a multifunctional regulator of cellular homeostasis, genome integrity, and stress response. NPM1 mutations, known as NPM1c variants promoting its aberrant cytoplasmic localization, are the...
4.
Alshamleh I, Kurrle N, Makowka P, Bhayadia R, Kumar R, Susser S, et al.
Leukemia
. 2023 Nov;
37(12):2367-2382.
PMID: 37935978
High metabolic flexibility is pivotal for the persistence and therapy resistance of acute myeloid leukemia (AML). In 20-30% of AML patients, activating mutations of FLT3, specifically FLT3-ITD, are key therapeutic...
5.
Koschade S, Moser L, Sokolovskiy A, Michael F, Serve H, Brandts C, et al.
J Clin Med
. 2023 Jul;
12(13).
PMID: 37445409
We performed a retrospective single-center analysis to investigate the diagnostic yield of bone marrow puncture in patients with liver cirrhosis and cytopenia. Liver cirrhosis patients receiving bone marrow aspiration or...
6.
Meyer L, Koschade S, Vischedyk J, Thoelken M, Gubas A, Wegner M, et al.
Autophagy
. 2023 Jul;
19(11):2982-2996.
PMID: 37439113
The selective autophagic degradation of mitochondria via mitophagy is essential for preserving mitochondrial homeostasis and, thereby, disease maintenance and progression in acute myeloid leukemia (AML). Mitophagy is orchestrated by a...
7.
Koschade S, Stratmann J, Zeiner P, Finkelmeier F, Chromik J, Steffen B, et al.
Ann Hematol
. 2023 Mar;
102(5):1045-1052.
PMID: 36947211
Cranial imaging (CI) is a widely used diagnostic procedure, especially in acute myeloid leukemia (AML) patients with suspected bleeding or infection. However, common clinical decision rules to guide CI do...
8.
Koschade S, Stratmann J, Steffen B, Shaid S, Finkelmeier F, Serve H, et al.
Eur J Haematol
. 2022 Dec;
110(4):426-434.
PMID: 36573351
Objectives And Methods: Venous thromboembolic (VTE) events are emerging as frequent complications in acute myeloid leukemia (AML); however, there is insufficient data regarding epidemiology, risk factors, and impact on outcomes....
9.
Koschade S, Klann K, Shaid S, Vick B, Stratmann J, Tholken M, et al.
Leukemia
. 2022 Nov;
36(12):2950.
PMID: 36347926
No abstract available.
10.
Koschade S, Tascher G, Parmar B, Brandts C, Munch C
J Proteome Res
. 2022 Oct;
21(11):2827-2835.
PMID: 36239476
Sample loss and contamination are critical preanalytical pitfalls in microscale proteomic applications of nonadhering cells. Common assays and workflows are not easily adoptable to microscale sample sizes of suspension cells...