Sebastian C Binder
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Explore the profile of Sebastian C Binder including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
544
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Recent Articles
11.
Arulraj T, Binder S, Robert P, Meyer-Hermann M
Front Immunol
. 2019 Sep;
10:2116.
PMID: 31555300
The germinal center reaction is an important target for modulating antibody responses. Antibody production from germinal centers is regulated by a negative feedback mechanism termed antibody feedback. By imposing antibody...
12.
Roco J, Mesin L, Binder S, Nefzger C, Gonzalez-Figueroa P, Canete P, et al.
Immunity
. 2019 Aug;
51(2):337-350.e7.
PMID: 31375460
Class-switch recombination (CSR) is a DNA recombination process that replaces the immunoglobulin (Ig) constant region for the isotype that can best protect against the pathogen. Dysregulation of CSR can cause...
13.
Meyer-Hermann M, Binder S, Mesin L, Victora G
Front Immunol
. 2018 Oct;
9:2020.
PMID: 30319600
Clonal evolution of B cells in germinal centers (GCs) is central to affinity maturation of antibodies in response to pathogens. Permanent or tamoxifen-induced multi-color recombination of B cells based on...
14.
Robert P, Rastogi A, Binder S, Meyer-Hermann M
Methods Mol Biol
. 2017 Jun;
1623:303-334.
PMID: 28589364
Germinal centers host a mini-evolutionary environment where B cells can mutate their receptor and be selected depending on its affinity to target antigens in a process called affinity maturation. Starting...
15.
Binder S, Meyer-Hermann M
Front Immunol
. 2017 Jan;
7:593.
PMID: 28066409
Intravital imaging of antibody optimization in germinal center (GC) reactions has set a new dimension in the understanding of the humoral immune response during the last decade. The inclusion of...
16.
Binder S, Eckweiler D, Schulz S, Bielecka A, Nicolai T, Franke R, et al.
Sci Rep
. 2016 Feb;
6:22212.
PMID: 26915971
The focus of modern molecular biology turns from assigning functions to individual genes towards understanding the expression and regulation of complex sets of molecules. Here, we provide evidence that alternative...
17.
Nguyen V, Binder S, Boianelli A, Meyer-Hermann M, Hernandez-Vargas E
Front Microbiol
. 2015 Apr;
6:257.
PMID: 25914675
The recent outbreaks of Ebola virus (EBOV) infections have underlined the impact of the virus as a major threat for human health. Due to the high biosafety classification of EBOV...
18.
Hernandez-Vargas E, Wilk E, Canini L, Toapanta F, Binder S, Uvarovskii A, et al.
J Virol
. 2014 Jan;
88(8):4123-31.
PMID: 24478442
Unlabelled: The consequences of influenza virus infection are generally more severe in individuals over 65 years of age (the elderly). Immunosenescence enhances the susceptibility to viral infections and renders vaccination...
19.
Binder S, Telschow A, Meyer-Hermann M
Front Microbiol
. 2012 Apr;
3:104.
PMID: 22470370
Many chronic inflammatory diseases are known to be caused by persistent bacterial or viral infections. A well-studied example is the tick-borne infection by the gram-negative spirochaetes of the genus Borrelia...