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Sebastian A Wohlfeil

Explore the profile of Sebastian A Wohlfeil including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 166
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Recent Articles
11.
Wohlfeil S, Hafele V, Dietsch B, Weller C, Sticht C, Jauch A, et al.
J Transl Med . 2022 Feb; 20(1):62. PMID: 35109875
Background: Cutaneous melanoma exhibits heterogeneous metastatic patterns and prognosis. In this regard, liver metastasis, which is detected in ~ 10-20% of stage 4 patients, came to the fore of melanoma...
12.
Olsavszky V, Sticht C, Schmid C, Winkler M, Wohlfeil S, Olsavszky A, et al.
Gene . 2020 Nov; 768:145284. PMID: 33130055
The Class H scavenger receptors Stabilin-1 (Stab1) and Stabilin-2 (Stab2) are two of the most highly expressed genes in liver sinusoidal endothelial cells (LSECs). While Stab1-deficient (Stab1KO) and Stab2-deficient (Stab2KO)...
13.
Wohlfeil S, Hafele V, Dietsch B, Schledzewski K, Winkler M, Zierow J, et al.
Cancer Res . 2018 Dec; 79(3):598-610. PMID: 30530502
The interaction of tumor cells with organ-specific endothelial cells (EC) is an important step during metastatic progression. Notch signaling in organ-specific niches has been implicated in mediating opposing effects on...
14.
Leibing T, Geraud C, Augustin I, Boutros M, Augustin H, Okun J, et al.
Hepatology . 2017 Oct; 68(2):707-722. PMID: 29059455
Conclusion: Angiocrine Wnt signaling controls liver growth as well as development of metabolic liver zonation in mice, whereas intrahepatic HEC zonation is not affected. (Hepatology 2017).
15.
Olsavszky V, Ulbrich F, Singh S, Diett M, Sticht C, Schmid C, et al.
Gene . 2017 Jul; 627:491-499. PMID: 28669928
Liver sinusoidal endothelial cells (LSEC) represent a unique, organ-specific type of discontinuous endothelial cells. LSEC instruct the hepatic vascular niche by paracrine-acting angiocrine factors. Recently, we have shown that LSEC-specific...
16.
Schonle A, Hartl F, Mentzel J, Noltner T, Rauch K, Prestipino A, et al.
Blood . 2016 Feb; 127(15):1930-9. PMID: 26837700
Caveolin-1 (Cav-1) is a key organizer of membrane specializations and a scaffold protein that regulates signaling in multiple cell types. We found increased Cav-1 expression in human and murine T...
17.
Klambt V, Wohlfeil S, Schwab L, Hulsdunker J, Ayata K, Apostolova P, et al.
J Immunol . 2015 Nov; 195(12):5795-804. PMID: 26538394
Acute graft-versus-host disease (GvHD) is a life-threatening complication of allogeneic hematopoietic cell transplantation. During the initiation phase of acute GvHD, endogenous danger signals such as ATP are released and inform...