Sebastian A Wagner
Overview
Explore the profile of Sebastian A Wagner including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
37
Citations
3432
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Wagner S
PeerJ
. 2022 Oct;
10:e14126.
PMID: 36275468
BRAF is a serine/threonine-specific protein kinase that regulates the MAPK/ERK signaling pathway, and mutations in the BRAF gene are considered oncogenic drivers in diverse types of cancer. Based on the...
2.
Graf J, Mikicic I, Ping X, Scalera C, Mayr K, Stelzl L, et al.
iScience
. 2022 Sep;
25(9):104892.
PMID: 36060052
PPM1D is a p53-regulated protein phosphatase that modulates the DNA damage response (DDR) and is frequently altered in cancer. Here, we employed chemical inhibition of PPM1D and quantitative mass spectrometry-based...
3.
Szczesniak P, Heidelberger J, Serve H, Beli P, Wagner S
PLoS One
. 2022 Apr;
17(4):e0266478.
PMID: 35385564
Acute myeloid leukemia (AML) is a heterogeneous malignancy characterized by the accumulation of undifferentiated white blood cells (blasts) in the bone marrow. Valosin-containing protein (VCP) is an abundant molecular chaperone...
4.
Li S, Silvestri V, Leslie G, Rebbeck T, Neuhausen S, Hopper J, et al.
J Clin Oncol
. 2022 Jan;
40(14):1529-1541.
PMID: 35077220
Purpose: To provide precise age-specific risk estimates of cancers other than female breast and ovarian cancers associated with pathogenic variants (PVs) in and for effective cancer risk management. Methods: We...
5.
Wagner S, Szczesniak P, Voigt A, Graf J, Beli P
Proteomics
. 2021 Mar;
21(10):e2000283.
PMID: 33768672
Kinase fusions are considered oncogenic drivers in numerous types of cancer. In lung adenocarcinoma 5-10% of patients harbor kinase fusions. The most frequently detected kinase fusion involves the Anaplastic Lymphoma...
6.
Parsons M, Tudini E, Li H, Hahnen E, Wappenschmidt B, Feliubadalo L, et al.
Hum Mutat
. 2019 May;
40(9):1557-1578.
PMID: 31131967
The multifactorial likelihood analysis method has demonstrated utility for quantitative assessment of variant pathogenicity for multiple cancer syndrome genes. Independent data types currently incorporated in the model for assessing BRCA1...
7.
Barth J, Abou-El-Ardat K, Dalic D, Kurrle N, Maier A, Mohr S, et al.
Leukemia
. 2019 Mar;
33(6):1541.
PMID: 30837671
The original version of this Article contained an error in the Acknowledgements section.
8.
Barth J, Abou-El-Ardat K, Dalic D, Kurrle N, Maier A, Mohr S, et al.
Leukemia
. 2019 Jan;
33(6):1411-1426.
PMID: 30679800
LSD1 has emerged as a promising epigenetic target in the treatment of acute myeloid leukemia (AML). We used two murine AML models based on retroviral overexpression of Hoxa9/Meis1 (H9M) or...
9.
Borisova M, Voigt A, Tollenaere M, Sahu S, Juretschke T, Kreim N, et al.
Nat Commun
. 2018 Mar;
9(1):1017.
PMID: 29523821
Ultraviolet (UV) light radiation induces the formation of bulky photoproducts in the DNA that globally affect transcription and splicing. However, the signaling pathways and mechanisms that link UV-light-induced DNA damage...
10.
Heidelberger J, Voigt A, Borisova M, Petrosino G, Ruf S, Wagner S, et al.
EMBO Rep
. 2018 Feb;
19(4).
PMID: 29467282
Valosin-containing protein (VCP) is an evolutionarily conserved ubiquitin-dependent ATPase that mediates the degradation of proteins through the ubiquitin-proteasome pathway. Despite the central role of VCP in the regulation of protein...