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Sean S Choi

Explore the profile of Sean S Choi including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 93
Followers 0
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Recent Articles
1.
Campbell C, Aich U, Weier C, Wang J, Choi S, Wen M, et al.
J Med Chem . 2008 Dec; 51(24):8135-47. PMID: 19053749
Per-butanoylated N-acetyl-D-mannosamine (Bu(4)ManNAc), a SCFA-hexosamine cancer drug candidate with activity manifest through intact n-butyrate-carbohydrate linkages, reduced the invasion of metastatic MDA-MB-231 breast cancer cells unlike per-butanoylated-D-mannose (Bu(5)Man), a clinically tested...
2.
Aich U, Campbell C, Elmouelhi N, Weier C, Sampathkumar S, Choi S, et al.
ACS Chem Biol . 2008 Mar; 3(4):230-40. PMID: 18338853
Chemical biology studies, exemplified by metabolic glycoengineering experiments that employ short chain fatty acid (SCFA)-hexosamine monosaccharide hybrid molecules, often suffer from off-target effects. Here we demonstrate that systematic structure-activity relationship...
3.
Sampathkumar S, Jones M, Meledeo M, Campbell C, Choi S, Hida K, et al.
Chem Biol . 2006 Dec; 13(12):1265-75. PMID: 17185222
Short-chain fatty acid (SCFA)-carbohydrate hybrid molecules that target both histone deacetylation and glycosylation pathways to achieve sugar-dependent activity against cancer cells are described in this article. Specifically, n-butyrate esters of...