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Sean M Fortier

Explore the profile of Sean M Fortier including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 113
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Recent Articles
1.
Baas J, Varga J, Feghali-Bostwick C, Peters-Golden M, Fortier S
bioRxiv . 2025 Mar; PMID: 40060695
Fibrosis in systemic sclerosis/scleroderma (SSc) is characterized by the progressive accumulation and persistence in multiple organs of pathologic fibroblasts whose contractile properties and exuberant secretion of collagens promote tissue stiffness...
2.
Fortier S, Walker N, Penke L, Baas J, Shen Q, Speth J, et al.
J Clin Invest . 2024 Mar; 134(10). PMID: 38512415
Fibrosis following tissue injury is distinguished from normal repair by the accumulation of pathogenic and apoptosis-resistant myofibroblasts (MFs), which arise primarily by differentiation from resident fibroblasts. Endogenous molecular brakes that...
3.
Penke L, Speth J, Huang S, Fortier S, Baas J, Peters-Golden M
JCI Insight . 2022 Jul; 7(16). PMID: 35852857
There is a paucity of information about potential molecular brakes on the activation of fibroblasts that drive tissue fibrosis. The transcription factor Krüppel-like factor 4 (KLF4) is best known as...
4.
Fortier S, Penke L, Peters-Golden M
Sci Adv . 2022 Mar; 8(12):eabp8322. PMID: 35319993
PGE and PGI receptors are potential targets for the treatment of chronic lung disease.
5.
Fortier S, Penke L, King D, Pham T, Ligresti G, Peters-Golden M
JCI Insight . 2021 Feb; 6(6). PMID: 33561015
Myofibroblasts are the major cellular source of collagen, and their accumulation - via differentiation from fibroblasts and resistance to apoptosis - is a hallmark of tissue fibrosis. Clearance of myofibroblasts...
6.
Cagino L, Hensley M, Fortier S, Dickson R
Am J Respir Crit Care Med . 2020 Mar; 201(8):992-994. PMID: 32126178
No abstract available.
7.
Koo S, Thomas H, David Daniels S, Lynch R, Fortier S, Shea M, et al.
Clin Infect Dis . 2014 Oct; 59(12):1733-40. PMID: 25342502
Background: Invasive aspergillosis (IA) remains a leading cause of mortality in immunocompromised patients, in part due to the difficulty of diagnosing this infection. Methods: Using thermal desorption-gas chromatography/mass spectrometry, we...
8.
Zurawel A, Walsh D, Fortier S, Chidawanyika T, Sengupta S, Zilm K, et al.
Biochemistry . 2013 Dec; 53(1):68-76. PMID: 24328062
Infectious mammalian prions can be formed de novo from purified recombinant prion protein (PrP) substrate through a pathway that requires the sequential addition of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol (POPG) and RNA cofactor molecules....