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Sean J Elliott

Explore the profile of Sean J Elliott including associated specialties, affiliations and a list of published articles. Areas
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Articles 72
Citations 1037
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Recent Articles
1.
Hewitt P, Hendrich M, Elliott S
Chem Sci . 2025 Mar; PMID: 40070466
Bacterial cytochrome peroxidase (bCcP) family members include di-heme enzymes that are capable of producing various high oxidation states in their reactions with the substrate HO. Canonical family members such as...
2.
Tracy M, Sosa Alfaro V, Campecino J, Hird K, Hegg E, Lehnert N, et al.
Biochemistry . 2025 Mar; PMID: 40026019
Cytochrome nitrite reductase (NrfA) is a pentaheme enzyme capable of the six-electron reduction of nitrite to ammonia, which is a key step in the nitrogen cycle. All NrfA enzymes appear...
3.
Bonitatibus S, Walker M, Elliott S
Methods Enzymol . 2024 Nov; 708:275-295. PMID: 39572143
The oxo-acid:ferredoxin oxidoreductase (OFOR) superfamily of enzymes are responsible for the reversible interconversion of CO and oxo-acids, using CoA-derivatives as co-substrates, and requiring redox equivalents in the form of a...
4.
Cossu M, Catlin D, Elliott S, Metcalf W, Nair S
Structure . 2024 Sep; 32(11):1963-1972.e3. PMID: 39265575
Enzymes of the 2-oxoacid:ferredoxin oxidoreductase (OFOR) superfamily catalyze the reversible oxidation of 2-oxoacids to acyl-coenzyme A esters and carbon dioxide (CO)using ferredoxin or flavodoxin as the redox partner. Although members...
5.
Gupta D, Chen K, Elliott S, Nayak D
Nat Commun . 2024 Apr; 15(1):3300. PMID: 38632227
Methanogens are a diverse group of Archaea that obligately couple energy conservation to the production of methane. Some methanogens encode alternate pathways for energy conservation, like anaerobic respiration, but the...
6.
Paris J, Hu S, Wen A, Weitz A, Cheng R, Gee L, et al.
Angew Chem Int Ed Engl . 2023 Aug; 62(43):e202309362. PMID: 37640689
Ergothioneine (ESH) and ovothiol A (OSHA) are two natural thiol-histidine derivatives. ESH has been implicated as a longevity vitamin and OSHA inhibits the proliferation of hepatocarcinoma. The key biosynthetic step...
7.
Hu W, Li K, Weitz A, Wen A, Kim H, Murray J, et al.
ACS Catal . 2023 May; 12(23):14559-14570. PMID: 37168530
Rieske-type non-heme iron oxygenases/oxidases catalyze a wide range of transformations. Their applications in bioremediation or biocatalysis face two key barriers: the need of expensive NAD(P)H as a reductant and a...
8.
Gupta D, Chen K, Elliott S, Nayak D
bioRxiv . 2023 May; PMID: 37131651
Methanogens are a diverse group of Archaea that couple energy conservation to the production of methane gas. While most methanogens have no alternate mode of energy conservation, strains like are...
9.
Pang H, Walker L, Silakov A, Zhang P, Yang W, Elliott S, et al.
J Am Chem Soc . 2021 Aug; 143(34):13835-13844. PMID: 34423974
The diversity of the reactions catalyzed by radical -adenosyl-l-methionine (SAM) enzymes is achieved at least in part through the variety of mechanisms to quench their radical intermediates. In the SPASM-twitch...
10.
Sosa Alfaro V, Campecino J, Tracy M, Elliott S, Hegg E, Lehnert N
Biochemistry . 2021 Jun; 60(23):1853-1867. PMID: 34061493
Cytochrome nitrite reductases (CNIR or NrfA) play important roles in the global nitrogen cycle by conserving the usable nitrogen in the soil. Here, the electron storage and distribution properties within...