Sean E Thatcher
Overview
Explore the profile of Sean E Thatcher including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
31
Citations
853
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Shridas P, Ji A, Trumbauer A, Noffsinger V, Leung S, Dugan A, et al.
Arterioscler Thromb Vasc Biol
. 2022 Mar;
42(5):632-643.
PMID: 35344382
Background: Obesity increases the risk for human abdominal aortic aneurysms (AAAs) and enhances Ang II (angiotensin II)-induced AAA formation in C57BL/6J mice. Obesity is also associated with increases in perivascular...
2.
AlSiraj Y, Thatcher S, Liang C, Ali H, Ensor M, Cassis L
J Pharmacol Exp Ther
. 2021 Mar;
377(3):326-335.
PMID: 33707301
Combined neprilysin (NEP) inhibition (sacubitril) and angiotensin type 1 receptor (AT1R) antagonism (valsartan) is used in the treatment of congestive heart failure and is gaining interest for other angiotensin II...
3.
AlSiraj Y, Thatcher S, Blalock E, Saintilnord W, Daugherty A, Lu H, et al.
Arterioscler Thromb Vasc Biol
. 2020 Oct;
41(1):269-283.
PMID: 33054396
Objective: Turner syndrome women (monosomy X) have high risk of aortopathies consistent with a role for sex chromosomes in disease development. We demonstrated that sex chromosomes influence regional development of...
4.
Shoemaker R, Tannock L, Su W, Gong M, Gurley S, Thatcher S, et al.
Biol Sex Differ
. 2019 Sep;
10(1):45.
PMID: 31484552
Background: Obesity increases the risk for hypertension in both sexes, but the prevalence of hypertension is lower in females than in males until menopause, despite a higher prevalence of obesity...
5.
Jackson E, Thatcher S, Larian N, English V, Soman S, Morris A, et al.
Environ Health Perspect
. 2019 Jul;
127(7):77004.
PMID: 31306034
Background: Lipophilic polychlorinated biphenyls (PCBs) accumulate with obesity, but during weight loss, liberated PCBs act as ligands of the aryl hydrocarbon receptor (AhR) to negatively influence health. Previous studies demonstrated...
6.
AlSiraj Y, Chen X, Thatcher S, Temel R, Cai L, Blalock E, et al.
Nat Commun
. 2019 Jun;
10(1):2631.
PMID: 31201301
Men and women differ in circulating lipids and coronary artery disease (CAD). While sex hormones such as estrogens decrease CAD risk, hormone replacement therapy increases risk. Biological sex is determined...
7.
Larian N, Ensor M, Thatcher S, English V, Morris A, Stromberg A, et al.
Food Chem Toxicol
. 2019 May;
130:219-230.
PMID: 31078726
Pseudomonas aeruginosa, a leading cause of sepsis, produces pyocyanin, a blue-pigmented virulence factor. Sepsis is associated with cachexia, but mechanisms are unknown and conventional nutrition approaches are not effective treatments....
8.
Stegbauer J, Thatcher S, Yang G, Bottermann K, Rump L, Daugherty A, et al.
J Vasc Surg
. 2019 Mar;
70(5):1658-1668.e1.
PMID: 30850299
Objective: Previous studies demonstrated that deficiency of angiotensin-converting enzyme 2 (ACE2) augmented angiotensin II (AngII)-induced atherosclerosis and abdominal aortic aneurysm (AAA) formation in hypercholesterolemic mice. Effects of ACE2 deficiency could...
9.
Sui Y, Liu Z, Park S, Thatcher S, Zhu B, Fernandez J, et al.
JCI Insight
. 2018 Jan;
3(2).
PMID: 29367460
Mesenchymal stem cells (MSCs) can give rise to both adipocytes and osteoblasts, but the molecular mechanisms underlying MSC fate determination remain poorly understood. IκB kinase β (IKKβ), a central coordinator...
10.
AlSiraj Y, Thatcher S, Blalock E, Fleenor B, Daugherty A, Cassis L
Arterioscler Thromb Vasc Biol
. 2017 Nov;
38(1):143-153.
PMID: 29097367
Objective: Aortic pathologies exhibit sexual dimorphism, with aneurysms in both the thoracic and abdominal aorta (ie, abdominal aortic aneurysm [AAA]) exhibiting higher male prevalence. Women have lower prevalence of aneurysms,...