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Sean E DeWolf

Explore the profile of Sean E DeWolf including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
DeWolf S, Hawkes A, Kurian S, Gorial D, Hepokoski M, Almeida S, et al.
Pulm Circ . 2024 Jul; 14(3):e12379. PMID: 38962184
Acute kidney injury (AKI) causes distant organ dysfunction through yet unknown mechanisms, leading to multiorgan failure and death. The lungs are one of the most common extrarenal organs affected by...
2.
DeWolf S, Kasimsetty S, Hawkes A, Stocks L, Kurian S, McKay D
Transplantation . 2021 Dec; 106(8):1589-1599. PMID: 34954736
Background: Renal ischemia-reperfusion injury (IRI) predictably causes acute kidney injury after shock and major cardiovascular procedures in all kidneys procured for transplantation. The earliest events of IRI are triggered by...
3.
Kasimsetty S, Hawkes A, DeWolf S, Welch A, McKay D
Transpl Immunol . 2021 Mar; 65:101348. PMID: 33706865
Pattern recognition receptors (PRRs) trigger adaptive inflammatory responses and as such are attractive targets for therapeutic manipulation of inflammation. In order to develop effective therapies however we need to understand...
4.
DeWolf S, Shigeoka A, Scheinok A, Kasimsetty S, Welch A, McKay D
Nephron . 2017 Jun; 137(1):68-76. PMID: 28614830
Background: Gender-biased outcomes are associated with acute kidney injury (AKI) and human and animal studies have shown that females are preferentially protected from renal ischemia. However, the reason for this...
5.
Kasimsetty S, DeWolf S, Shigeoka A, McKay D
Nephron Clin Pract . 2014 Oct; 127(1-4):119-23. PMID: 25343834
Pattern recognition receptors (PRRs) are now recognized to be key triggers of injury in a variety of renal diseases. Several families of these receptors are present in the kidney, and...