Sashi G Kasimsetty
Overview
Explore the profile of Sashi G Kasimsetty including associated specialties, affiliations and a list of published articles.
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13
Citations
321
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Recent Articles
1.
DeWolf S, Kasimsetty S, Hawkes A, Stocks L, Kurian S, McKay D
Transplantation
. 2021 Dec;
106(8):1589-1599.
PMID: 34954736
Background: Renal ischemia-reperfusion injury (IRI) predictably causes acute kidney injury after shock and major cardiovascular procedures in all kidneys procured for transplantation. The earliest events of IRI are triggered by...
2.
Kasimsetty S, Hawkes A, Barekatain K, Soo E, Welch A, McKay D
Transpl Immunol
. 2019 Nov;
58:101260.
PMID: 31760144
Pattern recognition receptors (PRRs) are potent triggers of tissue injury following renal ischemia/reperfusion injury (IRI). Specific PRRs, such as the toll-like receptor 2 (TLR2) and the nucleotide-binding oligomerization domain-like receptors...
3.
Kasimsetty S, Shigeoka A, Scheinok A, Gavin A, Ulevitch R, McKay D
J Immunol
. 2017 Jun;
199(3):1196-1205.
PMID: 28652394
Nucleotide-binding oligomerization domain (Nod)-containing proteins Nod1 and Nod2 play important roles in the innate immune response to pathogenic microbes, but mounting data suggest these pattern recognition receptors might also play...
4.
DeWolf S, Shigeoka A, Scheinok A, Kasimsetty S, Welch A, McKay D
Nephron
. 2017 Jun;
137(1):68-76.
PMID: 28614830
Background: Gender-biased outcomes are associated with acute kidney injury (AKI) and human and animal studies have shown that females are preferentially protected from renal ischemia. However, the reason for this...
5.
Kasimsetty S, McKay D
Curr Opin Nephrol Hypertens
. 2015 Dec;
25(1):3-11.
PMID: 26625866
Purpose Of Review: Ischemic injury inevitably occurs during the procurement of organs for transplantation, and the injury is worsened by inflammation following reperfusion. The purpose of this review is to...
6.
Kasimsetty S, Scheinok A, Shigeoka A, McKay D
Immunobiology
. 2015 Jul;
220(11):1227-31.
PMID: 26159289
Pattern recognition receptors (PRRs) play an important role in host anti-donor responses to transplanted tissue. A key trigger of the host alloresponse involves recognition of foreign antigen presented on activated...
7.
Kasimsetty S, DeWolf S, Shigeoka A, McKay D
Nephron Clin Pract
. 2014 Oct;
127(1-4):119-23.
PMID: 25343834
Pattern recognition receptors (PRRs) are now recognized to be key triggers of injury in a variety of renal diseases. Several families of these receptors are present in the kidney, and...
8.
Cheung K, Kasimsetty S, McKay D
Curr Opin Organ Transplant
. 2013 Jan;
18(2):154-60.
PMID: 23313940
Purpose Of Review: Ischaemic kidney injury occurs during organ procurement and can lead to delayed graft function or nonviable grafts. The innate immune system is a key trigger of inflammation...
9.
Bialonska D, Ramnani P, Kasimsetty S, Muntha K, Gibson G, Ferreira D
Int J Food Microbiol
. 2010 May;
140(2-3):175-82.
PMID: 20452076
We have examined the gut bacterial metabolism of pomegranate by-product (POMx) and major pomegranate polyphenols, punicalagins, using pH-controlled, stirred, batch culture fermentation systems reflective of the distal region of the...
10.
Kasimsetty S, Bialonska D, Reddy M, Ma G, Khan S, Ferreira D
J Agric Food Chem
. 2010 Feb;
58(4):2180-7.
PMID: 20112993
Pomegranate juice derived ellagitannins and their intestinal bacterial metabolites, urolithins, inhibited TCDD-induced CYP1-mediated EROD activity in vitro with IC(50) values ranging from 56.7 microM for urolithin A to 74.8 microM...