Se-Hoon Sim
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Explore the profile of Se-Hoon Sim including associated specialties, affiliations and a list of published articles.
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20
Citations
350
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Recent Articles
1.
Lee M, Joo M, Sim M, Sim S, Kim H, Lee J, et al.
Sci Rep
. 2019 Nov;
9(1):17257.
PMID: 31754158
Rapid modulation of RNA function by endoribonucleases during physiological responses to environmental changes is known to be an effective bacterial biochemical adaptation. We report a molecular mechanism underlying the regulation...
2.
Sim M, Lim B, Sim S, Kim D, Jung E, Lee Y, et al.
PLoS One
. 2014 Jun;
9(6):e100520.
PMID: 24956275
While identifying genes regulated by ribonuclease III (RNase III) in Escherichia coli, we observed that steady-state levels of betT mRNA, which encodes a transporter mediating the influx of choline, are...
3.
Song W, Kim Y, Sim S, Hwang S, Lee J, Lee Y, et al.
Nucleic Acids Res
. 2014 Feb;
42(7):4669-81.
PMID: 24489121
Here, we report a resistance mechanism that is induced through the modulation of 16S ribosomal RNA (rRNA) processing on the exposure of Escherichia coli cells to aminoglycoside antibiotics. We observed...
4.
Lim B, Sim S, Sim M, Kim K, Jeon C, Lee Y, et al.
J Bacteriol
. 2012 Feb;
194(9):2214-20.
PMID: 22343302
In Escherichia coli, the corA gene encodes a transporter that mediates the influx of Co(2+), Mg(2+), and Ni(2+) into the cell. During the course of experiments aimed at identifying RNase...
5.
Xu Y, Song S, Moeller A, Kim N, Piao S, Sim S, et al.
J Biol Chem
. 2011 Feb;
286(15):13541-9.
PMID: 21325274
Macrolide-specific efflux pump MacAB-TolC has been identified in diverse gram-negative bacteria including Escherichia coli. The inner membrane transporter MacB requires the outer membrane factor TolC and the periplasmic adaptor protein...
6.
Kim K, Sim S, Jeon C, Lee Y, Lee K
FEMS Microbiol Lett
. 2010 Dec;
315(1):30-7.
PMID: 21133991
RNase III, a double-stranded RNA-specific endoribonuclease, degrades bdm mRNA via cleavage at specific sites. To better understand the mechanism of cleavage site selection by RNase III, we performed a genetic...
7.
Kim H, Xu Y, Lee M, Piao S, Sim S, Ha N, et al.
J Bacteriol
. 2010 Jun;
192(17):4498-503.
PMID: 20581201
Tripartite efflux pumps found in Gram-negative bacteria are involved in antibiotic resistance and toxic-protein secretion. In this study, we show, using site-directed mutational analyses, that the conserved residues located in...
8.
Xu Y, Sim S, Song S, Piao S, Kim H, Jin X, et al.
Biochem Biophys Res Commun
. 2010 Mar;
394(4):962-5.
PMID: 20307498
The tripartite efflux pump MacAB-TolC found in gram-negative bacteria is involved in resistance to antibiotics. We previously reported the funnel-like hexameric structure of the adaptor protein MacA to be physiologically...
9.
Sim S, Yeom J, Shin C, Song W, Shin E, Kim H, et al.
Mol Microbiol
. 2009 Dec;
75(2):413-25.
PMID: 19943899
During the course of experiments aimed at identifying genes with ribonuclease III (RNase III)-dependent expression in Escherichia coli, we found that steady state levels of bdm mRNA were dependent on...
10.
Kim J, Sim S, Ha H, Ko J, Lee K, Bae J
FEBS Lett
. 2009 Aug;
583(17):2758-64.
PMID: 19683529
Myeloid cell leukemia-1 (MCL-1L) is a pro-survival member of the BCL-2 family that promotes cell survival. In this study, we identify a new splicing variant of human MCL-1 that encodes...