Scott W Boyer
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Explore the profile of Scott W Boyer including associated specialties, affiliations and a list of published articles.
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11
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1514
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Recent Articles
1.
Poscablo D, Worthington A, Smith-Berdan S, Rommel M, Manso B, Adili R, et al.
Cell
. 2024 May;
187(12):3090-3107.e21.
PMID: 38749423
Platelet dysregulation is drastically increased with advanced age and contributes to making cardiovascular disorders the leading cause of death of elderly humans. Here, we reveal a direct differentiation pathway from...
2.
Rodriguez Y Baena A, Rajendiran S, Manso B, Krietsch J, Boyer S, Kirschmann J, et al.
Sci Rep
. 2022 Feb;
12(1):3156.
PMID: 35210475
Hematopoietic stem cell (HSC) multipotency and self-renewal are typically defined through serial transplantation experiments. Host conditioning is necessary for robust HSC engraftment, likely by reducing immune-mediated rejection and by clearing...
3.
Rajendiran S, Boyer S, Forsberg E
Stem Cell Res
. 2021 Jan;
50:102145.
PMID: 33486300
Hematopoietic stem and progenitor cell (HSPC) transplantation is the paradigm for stem cell therapies. The protocol described here enables quantitative assessment of the body-wide HSPC reconstitution of different mature hematopoietic...
4.
Boyer S, Rajendiran S, Beaudin A, Smith-Berdan S, Muthuswamy P, Perez-Cunningham J, et al.
Stem Cell Reports
. 2019 Mar;
12(4):801-815.
PMID: 30905737
Hematopoiesis is arguably one of the best understood stem cell systems; however, significant challenges remain to reach a consensus understanding of the lineage potential, heterogeneity, and relationships of hematopoietic stem...
5.
Rodriguez D, Braden B, Boyer S, Taketa D, Setar L, Calhoun C, et al.
Mol Biol Cell
. 2017 Jun;
28(14):1883-1893.
PMID: 28615322
We investigated the physical role of the extracellular matrix (ECM) in vascular homeostasis in the basal chordate , which has a large, transparent, extracorporeal vascular network encompassing an area >100...
6.
Beaudin A, Boyer S, Perez-Cunningham J, Hernandez G, Derderian S, Jujjavarapu C, et al.
Cell Stem Cell
. 2016 Sep;
19(6):768-783.
PMID: 27666010
The generation of distinct hematopoietic cell types, including tissue-resident immune cells, distinguishes fetal from adult hematopoiesis. However, the mechanisms underlying differential cell production to generate a layered immune system during...
7.
Perez-Cunningham J, Boyer S, Landon M, Forsberg E
Exp Hematol
. 2016 May;
44(8):755-764.e1.
PMID: 27185381
Selective labeling of specific cell types by expression of green fluorescent protein (GFP) within the hematopoietic system would have great utility in identifying, localizing, and tracking different cell populations in...
8.
Beaudin A, Boyer S, Forsberg E
Exp Hematol
. 2013 Dec;
42(3):218-229.e4.
PMID: 24333663
Defining differentiation pathways is central to understanding the pathogenesis of hematopoietic disorders, including leukemia. The function of the receptor tyrosine kinase Flk2 (Flt3) in promoting myeloid development remains poorly defined,...
9.
Hashimoto D, Chow A, Noizat C, Teo P, Beasley M, Leboeuf M, et al.
Immunity
. 2013 Apr;
38(4):792-804.
PMID: 23601688
Despite accumulating evidence suggesting local self-maintenance of tissue macrophages in the steady state, the dogma remains that tissue macrophages derive from monocytes. Using parabiosis and fate-mapping approaches, we confirmed that...
10.
Boyer S, Beaudin A, Forsberg E
Cell Cycle
. 2012 Aug;
11(17):3180-8.
PMID: 22895180
Genetic fate-mapping approaches provide a unique opportunity to assess differentiation pathways under physiological conditions. We have recently employed a lineage tracing approach to define hematopoietic differentiation pathways in relation to...