Scott R Manson
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Explore the profile of Scott R Manson including associated specialties, affiliations and a list of published articles.
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21
Citations
313
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Recent Articles
1.
Lu Y, Manson S, De Araujo I, Austin P, Djurhuus J, Olsen L, et al.
Front Med (Lausanne)
. 2022 Jun;
9:892746.
PMID: 35646977
Bladder outlet obstruction (BOO) induces bladder dysfunction and altered bladder architecture. Irrespective of the release of the obstruction, persistent bladder dysfunction severely affects the quality of life. A better understanding...
2.
Wang X, Balaji S, Steen E, Blum A, Li H, Chan C, et al.
JCI Insight
. 2020 May;
5(12).
PMID: 32396531
Renal fibrosis features exaggerated inflammation, extracellular matrix (ECM) deposition, and peritubular capillary loss. We previously showed that IL-10 stimulates high-molecular weight hyaluronan (HMW-HA) expression by fibroblasts, and we hypothesize that...
3.
Dho S, Manson S, Jung S, Lim J, Weintraub S
Biochim Biophys Acta Mol Cell Res
. 2018 Apr;
1865(7):995-1001.
PMID: 29694915
In susceptible tumor cells, DNA-damaging antineoplastic agents induce an increase in intracellular pH during the premitochondrial stage of apoptosis. The rate of nonenzymatic deamidation of two asparagines in the anti-apoptotic...
4.
Kim Y, Park S, Manson S, Molina C, Kidd K, Thiessen-Philbrook H, et al.
JCI Insight
. 2017 Dec;
2(23).
PMID: 29212948
ER stress has emerged as a signaling platform underlying the pathogenesis of various kidney diseases. Thus, there is an urgent need to develop ER stress biomarkers in the incipient stages...
5.
Singh S, Manson S, Lee H, Kim Y, Liu T, Guo Q, et al.
PLoS One
. 2016 Jul;
11(7):e0158908.
PMID: 27454431
Emerging evidence has highlighted the pivotal role of microvasculature injury in the development and progression of renal fibrosis. Angiopoietin-1 (Ang-1) is a secreted vascular growth factor that binds to the...
6.
Kim Y, Lee H, Manson S, Lindahl M, Evans B, Miner J, et al.
J Am Soc Nephrol
. 2016 Mar;
27(10):2974-2982.
PMID: 26940092
Endoplasmic reticulum (ER) stress and disrupted proteostasis contribute to the pathogenesis of a variety of glomerular and tubular diseases. Thus, it is imperative to develop noninvasive biomarkers for detecting ER...
7.
Manson S, Austin P, Guo Q, Moore K
Vitam Horm
. 2015 Aug;
99:91-144.
PMID: 26279374
Chronic kidney disease (CKD) is a significant health problem that most commonly results from congenital abnormalities in children and chronic renal injury in adults. The therapeutic potential of BMP-7 was...
8.
Manson S, Song J, Guo Q, Liapis H, Austin P
J Urol
. 2015 Mar;
193(5 Suppl):1860-1869.
PMID: 25813565
Purpose: Congenital urinary tract obstruction is a leading cause of renal maldevelopment and pediatric kidney disease. Nonetheless, few groups have examined its molecular pathogenesis in humans. We evaluated the role...
9.
Guo Q, Tripathi P, Manson S, Austin P, Chen F
J Urol
. 2014 Oct;
193(5 Suppl):1784-90.
PMID: 25301096
Purpose: The calcineurin-NFAT signaling pathway regulates the transcription of genes important for development. It is impacted by various genetic and environmental factors. We investigated the potential role of NFAT induced...
10.
Dho S, Deverman B, Lapid C, Manson S, Gan L, Riehm J, et al.
PLoS Biol
. 2013 Jul;
11(6):e1001588.
PMID: 23823868
The cellular concentration of Bcl-xL is among the most important determinants of treatment response and overall prognosis in a broad range of tumors as well as an important determinant of...