Scott N Schneider
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Explore the profile of Scott N Schneider including associated specialties, affiliations and a list of published articles.
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15
Citations
600
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Recent Articles
1.
Macmillan D, Chilton M, Gao Y, Kern P, Schneider S
Regul Toxicol Pharmacol
. 2022 Aug;
135:105248.
PMID: 36007801
In June 2021 the Organisation for Economic Co-operation and Development published Guideline No. 497 on Defined Approaches for Skin Sensitisation (DASS GL). There are two DAs published, known as the...
2.
Schneider S, Liu Z, Wang B, Miller M, Afton S, Soleimani M, et al.
Int J Toxicol
. 2013 Dec;
33(1):14-20.
PMID: 24345748
The highly conserved human and mouse SLC39A8 gene encodes the divalent cation/bicarbonate symporter ZIP8 expressed ubiquitously in most cell types. Our bacterial artificial chromosome-transgenic BTZIP8-3 line has 3 additional copies...
3.
Kendig E, Chen Y, Krishan M, Johansson E, Schneider S, Genter M, et al.
Toxicol Appl Pharmacol
. 2011 Oct;
257(3):338-48.
PMID: 21967773
In humans and experimental animals, high fat diets (HFD) are associated with risk factors for metabolic diseases, such as excessive weight gain and adiposity, insulin resistance and fatty liver. Mice...
4.
Ma C, Schneider S, Miller M, Nebert D, Lind C, Roda S, et al.
J Biochem Mol Toxicol
. 2008 Oct;
22(5):305-10.
PMID: 18972394
There is evidence in human populations that exposure to manganese (Mn), or Mn in combination with excessive noise exposure, results in hearing loss. Quantitative reverse-transcriptase polymerase chain reaction revealed expression...
5.
Shertzer H, Schneider S, Kendig E, Clegg D, DAlessio D, Johansson E, et al.
Chem Biol Interact
. 2008 Oct;
177(1):71-80.
PMID: 18823964
Diabetes is characterized by elevated fasting blood glucose (FBG) resulting from improper insulin regulation and/or insulin resistance. Herein we used female C57BL/6J mouse models for type 1 diabetes (streptozotocin [STZ]...
6.
Over-the-counter analgesics normalize blood glucose and body composition in mice fed a high fat diet
Kendig E, Schneider S, Clegg D, Genter M, Shertzer H
Biochem Pharmacol
. 2008 Jun;
76(2):216-24.
PMID: 18554574
Type 2 diabetes (noninsulin-dependent diabetes mellitus) develops from a pre-diabetic condition that is characterized by insulin resistance and glucose intolerance, and is exacerbated by obesity. In this study, we compared...
7.
Shertzer H, Schneider S, Kendig E, Clegg D, DAlessio D, Genter M
Biochem Pharmacol
. 2008 Feb;
75(6):1402-10.
PMID: 18237716
Loss of pancreatic beta cell insulin secretion is the most important element in the progression of type 1 and type 2 diabetes. Since oxidative stress is involved in the progressive...
8.
Yang Y, Chen Y, Johansson E, Schneider S, Shertzer H, Nebert D, et al.
Biochem Pharmacol
. 2007 May;
74(2):372-81.
PMID: 17517378
Glutamate-cysteine ligase (GCL) is the rate-limiting enzyme in the glutathione (GSH) biosynthesis pathway. This enzyme is a heterodimer, comprising a catalytic subunit (GCLC) and a regulatory subunit (GCLM). Although GCLC...
9.
Chen Y, Yang Y, Miller M, Shen D, Shertzer H, Stringer K, et al.
Hepatology
. 2007 Apr;
45(5):1118-28.
PMID: 17464988
Unlabelled: Oxidative stress is considered to be a critical mediator in liver injury of various etiologies. Depletion of glutathione (GSH), the major antioxidant in liver, has been associated with numerous...
10.
Gao L, Wang J, Sekhar K, Yin H, Yared N, Schneider S, et al.
J Biol Chem
. 2006 Nov;
282(4):2529-37.
PMID: 17127771
Consumption of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can mitigate the progression of diseases in which oxidative stress represents a common underlying biochemical process. Nrf2-regulated gene expression regulates detoxification...