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Scott Latimer

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Articles 11
Citations 136
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Recent Articles
1.
Latimer S, Stutts L, Basset G
Phytochemistry . 2024 Jul; 226:114225. PMID: 39032792
The unprenylated benzoquinones 2,3,5,6-tetramethyl-1,4-benzoquinone (duroquinone), 2-chloro-1,4-benzoquinone (CBQ), 2,6-dimethyl-1,4-benzoquinone (DMBQ), 2,6-dichloro-1,4-benzoquinone (DCBQ), and 2,6-dimethoxy-1,4-benzoquinone (DMOBQ) were tested as putative antimetabolites of plastoquinone-9, a vital electron and proton carrier of oxygenic phototrophs....
2.
Stutts L, Latimer S, Batyrshina Z, Dickinson G, Alborn H, Block A, et al.
Plant Cell . 2023 Jul; 35(10):3686-3696. PMID: 37477936
Prenylated quinones are membrane-associated metabolites that serve as vital electron carriers for respiration and photosynthesis. The UbiE (EC 2.1.1.201)/MenG (EC 2.1.1.163) C-methyltransferases catalyze pivotal ring methylations in the biosynthetic pathways...
3.
Berger A, Latimer S, Stutts L, Soubeyrand E, Block A, Basset G
Curr Opin Plant Biol . 2022 Jan; 66:102165. PMID: 35026487
Ubiquinone (coenzyme Q) is a vital respiratory cofactor and liposoluble antioxidant. Studies have shown that plants derive approximately a quarter of 4-hydroxybenzoate, which serves as the direct ring precursor of...
4.
Latimer S, Keene S, Stutts L, Berger A, Bernert A, Soubeyrand E, et al.
J Biol Chem . 2021 Oct; 297(5):101283. PMID: 34626646
Ubiquinone (Coenzyme Q) is a vital respiratory cofactor and liposoluble antioxidant. In plants, it is not known how the C-6 hydroxylation of demethoxyubiquinone, the penultimate step in ubiquinone biosynthesis, is...
5.
Soubeyrand E, Latimer S, Bernert A, Keene S, Johnson T, Shin D, et al.
Phytochemistry . 2021 Mar; 186:112738. PMID: 33756238
Ubiquinone (Coenzyme Q) is a vital respiratory cofactor and antioxidant in eukaryotes. The recent discovery that kaempferol serves as a precursor for ubiquinone's benzenoid moiety both challenges the conventional view...
6.
Soubeyrand E, Kelly M, Keene S, Bernert A, Latimer S, Johnson T, et al.
Biochem J . 2019 Nov; 476(22):3521-3532. PMID: 31688904
Plants have evolved the ability to derive the benzenoid moiety of the respiratory cofactor and antioxidant, ubiquinone (coenzyme Q), either from the β-oxidative metabolism of p-coumarate or from the peroxidative...
7.
Soubeyrand E, Johnson T, Latimer S, Block A, Kim J, Colquhoun T, et al.
Plant Cell . 2018 Nov; 30(12):2910-2921. PMID: 30429224
Land plants possess the unique capacity to derive the benzenoid moiety of the vital respiratory cofactor, ubiquinone (coenzyme Q), from phenylpropanoid metabolism via β-oxidation of -coumarate to form 4-hydroxybenzoate. Approximately...
8.
Latimer S, Li Y, Nguyen T, Soubeyrand E, Fatihi A, Elowsky C, et al.
Plant J . 2018 May; 95(2):358-370. PMID: 29742810
The proteinogenic branched-chain amino acids (BCAAs) leucine, isoleucine and valine are essential nutrients for mammals. In plants, BCAAs double as alternative energy sources when carbohydrates become limiting, the catabolism of...
9.
Basset G, Latimer S, Fatihi A, Soubeyrand E, Block A
Mini Rev Med Chem . 2016 Jun; 17(12):1028-1038. PMID: 27337968
Background: Phylloquinone is a prenylated naphthoquinone that is synthesized exclusively by plants, green algae, and some species of cyanobacteria, where it serves as a vital electron carrier in photosystem I...
10.
Fatihi A, Latimer S, Schmollinger S, Block A, Dussault P, Vermaas W, et al.
Plant Cell . 2015 May; 27(6):1730-41. PMID: 26023160
Mutation of Arabidopsis thaliana NAD(P)H DEHYDROGENASE C1 (NDC1; At5g08740) results in the accumulation of demethylphylloquinone, a late biosynthetic intermediate of vitamin K1. Gene coexpression and phylogenomics analyses showed that conserved...