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Scott L Watson

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Articles 21
Citations 89
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Recent Articles
1.
Lynn S, Schultz I, Matten S, Patel P, Watson S, Yueh Y, et al.
Toxicol In Vitro . 2025 Mar; 106:106036. PMID: 40023338
The US Environmental Protection Agency is increasingly employing new approach methods (NAMs), including in vitro plasma binding and hepatocyte clearance experiments to collect chemical-species specific data. This paper presents data...
2.
Waidyanatha S, Black S, Witt K, Fennell T, Swartz C, Recio L, et al.
Xenobiotica . 2022 Apr; 52(3):301-311. PMID: 35473450
α-Pinene caused a concentration-responsive increase in bladder hyperplasia and decrease in sperm counts in rodents following inhalation exposure. Additionally, it formed a prospective reactive metabolite, α-pinene oxide.To provide human relevant...
3.
Mortensen N, Pathmasiri W, Snyder R, Moreno Caffaro M, Watson S, Patel P, et al.
Part Fibre Toxicol . 2022 Jan; 19(1):3. PMID: 34986857
Background: Nanoparticles (NPs) are increasingly incorporated in everyday products. To investigate the effects of early life exposure to orally ingested TiO NP, male and female Sprague-Dawley rat pups received four...
4.
Mortensen N, Moreno Caffaro M, Aravamudhan S, Beeravalli L, Prattipati S, Snyder R, et al.
Nanomaterials (Basel) . 2021 Jul; 11(6). PMID: 34199726
Oral exposure to nanoparticles (NPs) during early life is an understudied area. The goals of this study were to evaluate the effect of pre-weaned rat gastric fluids on 50 nm...
5.
Waidyanatha S, Hackett M, Black S, Stout M, Fennell T, Silinski M, et al.
Toxicol Appl Pharmacol . 2021 Mar; 418:115496. PMID: 33744279
The toxicokinetic behavior of α-pinene and its potential reactive metabolite, α-pinene oxide, was investigated following whole body inhalation exposure to 50 and 100 ppm α-pinene in rats and mice for...
6.
Marusich J, Gay E, Watson S, Blough B
Eur J Pharmacol . 2021 Feb; 897:173935. PMID: 33577836
Stimulant-induced neurochemical changes may occur at different times for different brain regions or neurotransmitter systems. This study sought to examine the behavioral and neurochemical effects of extended access to α-pyrrolidinopentiophenone...
7.
Fernando R, Fennell T, Watson S, Rehder Silinski M, Blake J, Robinson V, et al.
J Anal Toxicol . 2021 Jan; 46(3):270-276. PMID: 33438723
Alpha-pinene is a monoterpene found in the oil of coniferous trees and has a wide variety of applications. Alpha-pinene oxide (APO) is a potential reactive metabolite of alpha-pinene in rodents....
8.
Mortensen N, Moreno Caffaro M, Patel P, Snyder R, Watson S, Aravamudhan S, et al.
J Appl Toxicol . 2020 Dec; 41(8):1316-1329. PMID: 33269475
Little is known about the uptake, biodistribution, and biological responses of nanoparticles (NPs) and their toxicity in developing animals. Here, male and female juvenile Sprague-Dawley rats received four consecutive daily...
9.
Waidyanatha S, Black S, Patel P, Watson S, Snyder R, Sutherland V, et al.
Xenobiotica . 2020 Jun; 50(12):1469-1482. PMID: 32501182
Triclocarban is a residue-producing antibacterial agent used in a variety of consumer products. These studies investigated the disposition and metabolism of [C]triclocarban. In male rats following a single gavage administration...
10.
Waidyanatha S, Black S, Patel P, Rider C, Watson S, Snyder R, et al.
Toxicol Lett . 2019 Nov; 319:225-236. PMID: 31760063
N-Butylbenzenesulfonamide (NBBS) is a plasticizer detected in the environment suggesting potential human exposure. These studies investigated the in vitro hepatic clearance and disposition of [C]NBBS in rodents following a single...