Scott Kuersten
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Explore the profile of Scott Kuersten including associated specialties, affiliations and a list of published articles.
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39
Citations
2964
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Recent Articles
1.
Roos M, Bunga S, Tan A, Maissy E, Skola D, Richter A, et al.
bioRxiv
. 2025 Jan;
PMID: 39868335
Importance: Sequencing total RNA from microbiome samples is seriously impaired by the overwhelming proportion of rRNA to mRNA content. As much as 99% of sequencing reads can be assigned to...
2.
Maghini D, Dvorak M, Dahlen A, Roos M, Doyle B, Kuersten S, et al.
Nat Biotechnol
. 2024 Jul;
42(8):1313.
PMID: 39048712
No abstract available.
3.
Broad variation in response of individual introns to splicing inhibitors in a humanized yeast strain
Hunter O, Talkish J, Quick-Cleveland J, Igel H, Tan A, Kuersten S, et al.
RNA
. 2023 Dec;
30(2):149-170.
PMID: 38071476
Intron branchpoint (BP) recognition by the U2 snRNP is a critical step of splicing, vulnerable to recurrent cancer mutations and bacterial natural product inhibitors. The BP binds a conserved pocket...
4.
Broad variation in response of individual introns to splicing inhibitors in a humanized yeast strain
Hunter O, Talkish J, Quick-Cleveland J, Igel H, Tan A, Kuersten S, et al.
bioRxiv
. 2023 Oct;
PMID: 37873484
Intron branch point (BP) recognition by the U2 snRNP is a critical step of splicing, vulnerable to recurrent cancer mutations and bacterial natural product inhibitors. The BP binds a conserved...
5.
Tan A, Murugapiran S, Mikalauskas A, Koble J, Kennedy D, Hyde F, et al.
BMC Microbiol
. 2023 Oct;
23(1):299.
PMID: 37864136
The microbiota that colonize the human gut and other tissues are dynamic, varying both in composition and functional state between individuals and over time. Gene expression measurements can provide insights...
6.
Natarajan A, Fremin B, Schmidtke D, Wolfe M, Zlitni S, Graham K, et al.
Appl Environ Microbiol
. 2023 Jul;
89(7):e0058323.
PMID: 37404180
Microbial source tracking (MST) identifies sources of fecal contamination in the environment using host-associated fecal markers. While there are numerous bacterial MST markers that can be used herein, there are...
7.
Koffa M, Clements J, Izaurralde E, Wadd S, Wilson S, Mattaj I, et al.
EMBO J
. 2023 Jun;
42(14):e114021.
PMID: 37376956
No abstract available.
8.
Dhondt B, Pinheiro C, Geeurickx E, Tulkens J, Vergauwen G, van der Pol E, et al.
J Extracell Vesicles
. 2023 May;
12(5):e12315.
PMID: 37202906
The analysis of extracellular vesicles (EV) in blood samples is under intense investigation and holds the potential to deliver clinically meaningful biomarkers for health and disease. Technical variation must be...
9.
Maghini D, Dvorak M, Dahlen A, Roos M, Doyle B, Kuersten S, et al.
Nat Biotechnol
. 2023 Apr;
42(2):328-338.
PMID: 37106038
To gain insight into the accuracy of microbial measurements, it is important to evaluate sources of bias related to sample condition, preservative method and bioinformatic analyses. There is increasing evidence...
10.
Natarajan A, Fremin B, Schmidtke D, Wolfe M, Zlitni S, Graham K, et al.
bioRxiv
. 2023 Jan;
PMID: 36712100
Importance: Human exposure to fecal contamination in the environment can cause transmission of infectious diseases. Microbial source tracking (MST) can identify sources of fecal contamination so that contamination can be...