Scott K Durum
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Explore the profile of Scott K Durum including associated specialties, affiliations and a list of published articles.
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78
Citations
3807
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Recent Articles
1.
Kline S, Orlando N, Lee A, Wu M, Zhang J, Youn C, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(6):e2309243121.
PMID: 38289950
skin colonization and eosinophil infiltration are associated with many inflammatory skin disorders, including atopic dermatitis, bullous pemphigoid, Netherton's syndrome, and prurigo nodularis. However, whether there is a relationship between and...
2.
Chen K, McCulloch J, Das Neves R, Rodrigues G, Hsieh W, Gong W, et al.
Gut Pathog
. 2023 Dec;
15(1):60.
PMID: 38037170
No abstract available.
3.
Winer H, Li W, Rodrigues G, Gower T, Meyer T, Hixon J, et al.
Haematologica
. 2023 Nov;
109(6):1726-1740.
PMID: 38031763
Acute lymphoblastic leukemia (ALL) is an aggressive leukemia which can be derived from either T-cell or B-cell precursors. With current treatments, the survival rate is high, but the treatments are...
4.
Rana S, Dranchak P, Dahlin J, Lamy L, Li W, Oliphant E, et al.
Cell Chem Biol
. 2023 Oct;
31(2):221-233.e14.
PMID: 37875111
Methotrexate (MTX) is a tight-binding dihydrofolate reductase (DHFR) inhibitor, used as both an antineoplastic and immunosuppressant therapeutic. MTX, like folate undergoes folylpolyglutamate synthetase-mediated γ-glutamylation, which affects cellular retention and target...
5.
Rodrigues G, Li W, Cramer S, Winer H, Hsu T, Gower T, et al.
J Vis Exp
. 2023 Jun;
(196).
PMID: 37358271
Transduced mouse immature thymocytes can be differentiated into T cells in vitro using the delta-like 4-expressing bone marrow stromal cell line co-culture system (OP9-DL4). As retroviral transduction requires dividing cells...
6.
Chen K, McCulloch J, Das Neves R, Rodrigues G, Hsieh W, Gong W, et al.
Gut Pathog
. 2023 Jun;
15(1):28.
PMID: 37322488
Background: Formyl peptide receptor 2 (Fpr2) plays a crucial role in colon homeostasis and microbiota balance. Commensal E. coli is known to promote the regeneration of damaged colon epithelial cells....
7.
Andrews C, McLean M, Hixon J, Pontejo S, Starr T, Malo C, et al.
Front Immunol
. 2023 May;
14:1021824.
PMID: 37153622
Mucosal delivery of IL-27 has been shown to have a therapeutic benefit in murine models of inflammatory bowel disease (IBD). The IL-27 effect was associated with phosphorylated STAT1 (pSTAT1), a...
8.
Hsu T, Rodrigues G, Winer H, Hixon J, Li W, Tarasova N, et al.
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36675167
Four Ras guanine nucleotide-releasing proteins (RasGRP1 through 4) belong to the family of guanine nucleotide exchange factors (GEFs). RasGRPs catalyze the release of GDP from small GTPases Ras and Rap...
9.
Winer H, Rodrigues G, Hixon J, Aiello F, Hsu T, Wachter B, et al.
Cytokine
. 2022 Oct;
160:156049.
PMID: 36201890
Overview: IL-7 is a member of the family of cytokines with four anti-parallel α helixes that bind Type I cytokine receptors. It is produced by stromal cells and is required...
10.