Scott F Hickey
Overview
Explore the profile of Scott F Hickey including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
160
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0
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Recent Articles
1.
Su Y, Hickey S, Keyser S, Hammond M
J Am Chem Soc
. 2016 May;
138(22):7040-7.
PMID: 27191512
High-throughput enzyme activity screens are essential for target characterization and drug development, but few assays employ techniques or reagents that are applicable to both in vitro and live cell settings....
2.
Kellenberger C, Wilson S, Hickey S, Gonzalez T, Su Y, Hallberg Z, et al.
Proc Natl Acad Sci U S A
. 2015 Apr;
112(17):5383-8.
PMID: 25848022
Cyclic dinucleotides are an expanding class of signaling molecules that control many aspects of bacterial physiology. A synthase for cyclic AMP-GMP (cAG, also referenced as 3'-5', 3'-5' cGAMP) called DncV...
3.
Hickey S, Hammond M
Chem Biol
. 2014 Feb;
21(3):345-56.
PMID: 24560607
Many classes of S-adenosylmethionine (SAM)-binding RNAs and proteins are of interest as potential drug targets in diverse therapeutic areas, from infectious diseases to cancer. In the former case, the SAM-I...
4.
Karns K, Vogan J, Qin Q, Hickey S, Wilson S, Hammond M, et al.
J Am Chem Soc
. 2013 Jan;
135(8):3136-43.
PMID: 23343213
Riboswitches are RNA sensors that change conformation upon binding small molecule metabolites, in turn modulating gene expression. Our understanding of riboswitch regulatory function would be accelerated by a high-throughput, quantitative...
5.
Hickey S, Sridhar M, Westermann A, Qin Q, Vijayendra P, Liou G, et al.
Nucleic Acids Res
. 2012 Feb;
40(10):4701-10.
PMID: 22311854
Compared to transcriptional activation, other mechanisms of gene regulation have not been widely exploited for the control of transgenes. One barrier to the general use and application of alternative splicing...
6.
Rose C, Hayes M, Stettler G, Hickey S, Axelrod T, Giustini N, et al.
Analyst
. 2010 Sep;
135(11):2945-51.
PMID: 20820497
The emergence of functional genomics and proteomics has added to the growing need for improved analysis methods that can detect and distinguish between protein variants resulting from allelic variation, mutation,...