Scott D Sorensen
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Explore the profile of Scott D Sorensen including associated specialties, affiliations and a list of published articles.
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7
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251
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Recent Articles
1.
Ignar D, Goetz A, Noble K, Carballo L, Stroup A, Fisher J, et al.
J Pharmacol Exp Ther
. 2011 Jun;
339(1):24-34.
PMID: 21712426
μ-Opioid receptor (MOR) agonism induces palatable food consumption principally through modulation of the rewarding properties of food. N-{[3,5-difluoro-3'-(1H-1,2,4-triazol-3-yl)-4-biphenylyl]methyl}-2,3-dihydro-1H-inden-2-amine (GSK1521498) is a novel opioid receptor inverse agonist that, on the basis...
2.
Murray D, Johnson E, Wang P, Gauthier J, Bing N, Vanderwall D, et al.
J Recept Signal Transduct Res
. 2009 Jul;
29(5):246-56.
PMID: 19627252
Interleukin-1 (IL-1alpha) induced inflammatory and pro-fibrotic responses in human lung fibroblasts are mediated by activation of MAPK and NFkappaB pathways. The purpose of the present study was to broadly profile...
3.
Nicole O, Goldshmidt A, Hamill C, Sorensen S, Sastre A, Lyuboslavsky P, et al.
J Neurosci
. 2005 Apr;
25(17):4319-29.
PMID: 15858058
We have studied the involvement of the thrombin receptor [protease-activated receptor-1 (PAR-1)] in astrogliosis, because extravasation of PAR-1 activators, such as thrombin, into brain parenchyma can occur after blood-brain barrier...
4.
Sorensen S, Nicole O, Peavy R, Montoya L, Lee C, Murphy T, et al.
Mol Pharmacol
. 2003 Oct;
64(5):1199-209.
PMID: 14573770
Receptors for the serine protease thrombin and for lysophospholipids are coupled to G proteins and control a wide range of cellular functions, including mitogenesis. Activators of these receptors are present...
5.
Sorensen S, Conn P
Neuropharmacology
. 2003 Apr;
44(6):699-706.
PMID: 12681368
Metabotropic glutamate receptors (mGluR) serve important neuromodulatory roles at glutamatergic synapses to shape excitatory neurotransmission. Recent evidence indicates that the desensitization of mGluRs is an important determinant in regulating the...
6.
Peavy R, Sorensen S, Conn P
J Neurochem
. 2002 Oct;
83(1):110-8.
PMID: 12358734
The metabotropic glutamate receptor 5 (mGluR5) exhibits a rapid loss of receptor responsiveness to prolonged or repeated agonist exposure. This receptor desensitization has been seen in a variety of native...
7.
Sorensen S, Macek T, Cai Z, Saugstad J, Conn P
Mol Pharmacol
. 2002 May;
61(6):1303-12.
PMID: 12021391
Presynaptic metabotropic glutamate receptors (mGluRs) often act as feedback inhibitors of synaptic transmission and serve important roles in defining the activity of glutamatergic synapses. Recent investigations have begun to identify...