Scott C Garman
Overview
Explore the profile of Scott C Garman including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
32
Citations
1002
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Sawyer T, Aral E, Staros J, Bobst C, Garman S
bioRxiv
. 2024 Apr;
PMID: 38617236
Sphingolipid activator protein B (saposin B; SapB) is an essential activator of globotriaosylceramide (Gb3) catabolism by α-galactosidase A. However, the manner by which SapB stimulates α-galactosidase A activity remains unknown....
2.
Nguyen B, Ozden C, Dong K, Torres-Ocampo A, Dziedzic N, Flaherty D, et al.
bioRxiv
. 2024 Apr;
PMID: 38585726
Ca signaling plays a key role in physiological processes such as memory formation and cardiac function. Ca/calmodulin-dependent protein kinase II (CaMKII) is the primary kinase that responds to Ca inputs...
3.
Ozden C, MacManus S, Adafia R, Samkutty A, Torres-Ocampo A, Garman S, et al.
Protein Sci
. 2024 Mar;
33(4):e4960.
PMID: 38501502
Ca /calmodulin-dependent protein kinase II (CaMKII) is a multidomain serine/threonine kinase that plays important roles in the brain, heart, muscle tissue, and eggs/sperm. The N-terminal kinase and regulatory domain is...
4.
Ozden C, Sloutsky R, Mitsugi T, Santos N, Agnello E, Gaubitz C, et al.
Cell Rep
. 2022 Jul;
40(2):111064.
PMID: 35830796
Ca/calmodulin-dependent protein kinase II (CaMKII) is a signaling protein required for long-term memory. When activated by Ca/CaM, it sustains activity even after the Ca dissipates. In addition to the well-known...
5.
Torres-Ocampo A, Ozden C, Hommer A, Gardella A, Lapinskas E, Samkutty A, et al.
Protein Sci
. 2020 Apr;
29(6):1524-1534.
PMID: 32282091
Ca /calmodulin-dependent protein kinase II (CaMKII) is a Ser/Thr kinase necessary for long-term memory formation and other Ca -dependent signaling cascades such as fertilization. Here, we investigated the stability of...
6.
Germain D, Brand E, Burlina A, Cecchi F, Garman S, Kempf J, et al.
Mol Genet Genomic Med
. 2018 Apr;
PMID: 29649853
Background: The p.Asn215Ser or p.N215S GLA variant has been associated with late-onset cardiac variant of Fabry disease. Methods: To expand on the scarce phenotype data, we analyzed natural history data...
7.
Hingorani K, Metcalf M, Deming D, Garman S, Powers E, Gierasch L
Nat Chem Biol
. 2017 Feb;
13(4):369-371.
PMID: 28218913
Protein folding in cells occurs in the presence of high concentrations of endogenous binding partners, and exogenous binding partners have been exploited as pharmacological chaperones. A combined mathematical modeling and...
8.
Zhou Y, Metcalf M, Garman S, Edmunds T, Qiu H, Wei R
Nat Commun
. 2016 Oct;
7:13082.
PMID: 27725636
Acid sphingomyelinase (ASM) hydrolyzes sphingomyelin to ceramide and phosphocholine, essential components of myelin in neurons. Genetic alterations in ASM lead to ASM deficiency (ASMD) and have been linked to Niemann-Pick...
9.
Ryan K, Guce A, Johnson O, Brunold T, Cabelli D, Garman S, et al.
Biochemistry
. 2015 Jan;
54(4):1016-27.
PMID: 25580509
Crystal structures of nickel-dependent superoxide dismutases (NiSODs) reveal the presence of a H-bonding network formed between the NH group of the apical imidazole ligand from His1 and the Glu17 carboxylate...
10.
Ferreira S, Ortiz A, Germain D, Viana-Baptista M, Caldeira-Gomes A, Camprecios M, et al.
Mol Genet Metab
. 2014 Dec;
114(2):248-58.
PMID: 25468652
Lysosomal α-galactosidase A (α-Gal) is the enzyme deficient in Fabry disease (FD), an X-linked glycosphingolipidosis caused by pathogenic mutations affecting the GLA gene. The early-onset, multi-systemic FD classical phenotype is...