Scott A Nichols
Overview
Explore the profile of Scott A Nichols including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
476
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0
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Recent Articles
1.
Ruperti F, Dzieciatkowska M, Pankey M, Asensio C, Anselmetti D, Fernandez-Busquets X, et al.
Proc Natl Acad Sci U S A
. 2024 Dec;
121(52):e2409125121.
PMID: 39693348
The discovery that sponges (Porifera) can fully regenerate from aggregates of dissociated cells launched them as one of the earliest experimental models to study the evolution of cell adhesion and...
2.
Green K, Roth-Carter Q, Niessen C, Nichols S
Curr Biol
. 2020 May;
30(10):R535-R543.
PMID: 32428495
Cadherin-based cell-cell junctions help metazoans form polarized sheets of cells, which are necessary for the development of organs and the compartmentalization of functions. The components of the protein complexes that...
3.
Mitchell J, Nichols S
Evodevo
. 2019 Nov;
10:26.
PMID: 31687123
The integrity and organization of animal tissues depend upon specialized protein complexes that mediate adhesion between cells with each other (cadherin-based adherens junctions), and with the extracellular matrix (integrin-based focal...
4.
Colgren J, Nichols S
Wiley Interdiscip Rev Dev Biol
. 2019 Jul;
9(2):e359.
PMID: 31352684
Sponges, ctenophores, placozoans, and cnidarians have key evolutionary significance in that they bracket the time interval during which organized animal tissues were first assembled, fundamental cell types originated (e.g., neurons...
5.
6.
Miller P, Pokutta S, Mitchell J, Chodaparambil J, Clarke D, Nelson W, et al.
J Biol Chem
. 2018 Jun;
293(30):11674-11686.
PMID: 29880641
The evolution of cell-adhesion mechanisms in animals facilitated the assembly of organized multicellular tissues. Studies in traditional animal models have revealed two predominant adhesion structures, the adherens junction (AJ) and...
7.
Schippers K, Nichols S
Mol Biol Evol
. 2018 Mar;
35(6):1407-1421.
PMID: 29522209
β-Catenin acts as a transcriptional coactivator in the Wnt/β-catenin signaling pathway and a cytoplasmic effector in cadherin-based cell adhesion. These functions are ancient within animals, but the earliest steps in...
8.
Ereskovsky A, Richter D, Lavrov D, Schippers K, Nichols S
PLoS One
. 2017 Sep;
12(9):e0183002.
PMID: 28892487
The homoscleromorph sponge Oscarella carmela, first described from central California, USA is shown to represent two superficially similar but both morphologically and phylogenetically distinct species that are co-distributed. We here...
9.
Pena J, Alie A, Richter D, Wang L, Funayama N, Nichols S
Evodevo
. 2016 Jul;
7:13.
PMID: 27413529
Background: The microvillus is a versatile organelle that serves important functions in disparate animal cell types. However, from a molecular perspective, the microvillus has been well studied in only a...
10.
Schippers K, Nichols S
Cell
. 2014 Sep;
159(1):9-10.
PMID: 25259913
Tosches et al. show that melatonin signaling regulates circadian swimming in annelid worms by rhythmically activating cholinergic neurons. This suggests an evolutionary connection between melatonin signaling in invertebrates and sleep...